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Key Principles in Pharmacogenomics

Learning Objectives
1. Describe the basic principles and concepts in pharmacogenomics
2. Discuss the relevance of pharmacogenomics in medicine today
3. Discuss drivers and barriers of clinical implementation of pharmacogenomics
0.5 Credit CME
Key Principles in Pharmacogenomics

The unprecedented, rapid advances in genetic and genomic knowledge, information and technologies have made it challenging for primary care and other nongenetics health care providers to stay current on recommendations and practices in clinical genetics. To address this education gap for nongenetics providers and to foster the effective integration of those advances into the broad clinical practice of primary care and specialty health care providers, the American College of Medical Genetics and Genomics (ACMG) has created a formal online accredited continuing education offering, “ACMG Genetics 101 for Healthcare Providers.” In each module of the course, a board-certified medical genetics expert will provide a case-based presentation, along with supporting reading materials.

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American College of Medical Genetics and Genomics (ACMG) is a professional membership organization that provides education, resources and a voice for the medical genetics profession. Learn more.

Article Information

© 2022 American College of Medical Genetics and Genomics. All rights reserved.

Genetics101 for Healthcare Providers

Date of Release: 2/1/2022

Expiration Date: 2/1/2025

Credits offered: .5 per module

Estimate time of completion: 5 hours

Course/Module must be completed by the expiration date

This course is supported by an independent medical education grant from Illumina, Inc.

Target Audience:

This course is primarily for the non-geneticist health care professional.


The American College of Medical Genetics and Genomics is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Credit Designation Statement: The American College of Medical Genetics and Genomics designates this online enduring activity for a maximum of 0.50 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Accredited Continuing Education Financial Disclosure

The American College of Medical Genetics and Genomics (ACMG) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide Accredited Continuing Education (ACE) for physicians. ACMG is an organization committed to improvement of patient care and general health by the incorporation of genetics and genomics into clinical practice.

ACMG has implemented the following procedures to ensure the independence of ACE activities from commercial influence/promotional bias, the Accreditation Council for Continuing Medical Education (ACCME) requires that providers (ACMG) must be able to demonstrate that: 1) everyone in a position to control the content of an ACE activity has disclosed all financial relationships that they have had in the past 24 months with ineligible* companies; 2) ACMG has implemented a mechanism to mitigate relevant financial relationships; and 3) all relevant financial relationships with ineligible companies are disclosed to the learners before the beginning of the educational activity. The learners must also be informed if no relevant financial relationships exist.

*Ineligible companies are defined as those whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

ACMG Education Policies

Please review the policies below regarding the ACMG Education program

Financial Disclosures and Mitigation Procedure

ACMG Content Validation Policy

ACMG Content Branding Policy

Financial Support Disclosure Statement: The following course director, program planning committee members, speakers, and staff for this activity, have no financial relationships with ineligible companies relevant to the content of this course.

Aniwaa Owusu Obeng, PharmD

Icahn School of Medicine at Mount Sinai

Nothing to disclose

Content Contributors

Aniwaa Owusu Obeng, PharmD

Assistant Professor, Icahn School of Medicine at Mount Sinai

Dr. Aniwaa Owusu Obeng is a faculty member of the Charles Bronfman Institute for Personalized Medicine and an Assistant Professor in the Departments of Medicine and Genetics and Genomics Sciences at the Icahn School of Medicine at Mount Sinai (ISMMS) in New York, USA. She also has an appointment in The Mount Sinai Hospital as the Clinical Pharmacogenomics Coordinator. Dr. Obeng joined Mount Sinai in July 2013 and has been spearheading clinical pharmacogenomics implementation efforts in Mount Sinai's outpatient clinics ever since. As part of this initiative, physicians are trained to use genetic information to inform their prescribing decisions for approximately 2000 preemptively genotyped patients and counting. She has also led the development of provider and patient educational materials and tools on pharmacogenomics as part of this effort. Moreover, Dr. Owusu Obeng directs clinical pharmacogenomics rotations for PGY1 and PGY2 pharmacy residents in the Mount Sinai Health System and Advanced Pharmacy Practice Experience (APPE) rotation for final year student pharmacists.

Dr. Owusu Obeng obtained her Doctor of Pharmacy degree from the Albany College of Pharmacy and Health Sciences in Albany, NY. She then pursued a clinical residency (PGY1) in general pharmacy practice at the BronxLebanon Hospital Center in Bronx, NY, and subsequently, PGY2 at the University of Florida College of Pharmacy and UF Health Shands Hospital in Gainesville, Florida. As the inaugural resident in the UF Health Personalized Medicine Program, Dr. Owusu Obeng specialized in Pharmacogenomics and Drug Information. Dr. Obeng has published over 30 peer-reviewed manuscripts and book chapters on pharmacogenomics and precision medicine. She is a guideline writing member of the Clinical Pharmacogenetics Implementation Consortium (CPIC); member of the Pharmacogenomics Working Group in the NIH/NHGRI – funded IGNITE (Implementing Genomics in Practice) Network; 2017 ISMMS Leadership Emerging in Academic Departments (LEAD) Scholar; and a member and 2017 MERIT Scholar of the American College of Clinical Pharmacy (ACCP). Her research interests mainly lie in bridging the gap between discovery of genetic determinants of therapeutic response and clinical implementation by developing best practice processes to effectively adopt genomic medicine into everyday clinical practice.

Peer Review

In December of 2021, this continuing medical education online enduring activity was reviewed by Drs. Shweta Dhar and Fuki Hisama. To ensure the continued scientific relevance of this enduring material, its content will be reviewed again prior to the expiry date.


ACMG educational programs are designed primarily as an educational tool for health care providers who wish to increase their understanding of the application of genomic technologies to patient care. The ACMG does not endorse or recommend the use of this educational program to make patient diagnoses, particular by individuals not trained in medical genetics. Adherence to the information provided in these programs does not necessarily ensure a successful diagnostic outcome. The program should not be considered inclusive of all proper procedures and or exclusive of other procedures and that are reasonably directed at obtaining the same results. In determining the propriety of any specific procedure or, a healthcare provider should apply his or her own professional judgment to the specific clinical circumstances presented by the individual patient or specimen.

Questions regarding CE credit should be directed to education@acmg.net


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