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Oral and Penile Lesions in a Young Man

Educational Objective
Based on this clinical scenario and the accompanying image, understand how to arrive at a correct diagnosis.
1 Credit CME

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Article Information

Corresponding Author: Franco Falcone, MD, Department of Medicine, State University of New York Downstate Medical Center, 450 Clarkson Ave, MSC-50, Brooklyn, NY 11203 (franco.falcone@nychhc.org).

Published Online: June 24, 2019. doi:10.1001/jama.2019.7804

Conflict of Interest Disclosures: None reported.

Additional Contributions: We thank Christopher Torsitano, BS, and Barrett Torre, BA (College of Medicine, State University of New York, Downstate Medical Center), for help with the literature review; Silvia Mancebo, MD, and Miriam Lieberman, MD (Department of Dermatology, State University of New York, Downstate Medical Center), for help with photograph acquisition; and Samy McFarlane, MD, MPH, MBA (Department of Internal Medicine, State University of New York, Downstate Medical Center), for help with the overall content and editorial review. None of these individuals received compensation for their contributions. We also thank the patient for providing permission to share his information.

References
1.
Canavan  TN, Mathes  EF, Frieden  I, Shinkai  K.  Mycoplasma pneumoniae-induced rash and mucositis as a syndrome distinct from Stevens-Johnson syndrome and erythema multiforme: a systematic review.  J Am Acad Dermatol. 2015;72(2):239-245. doi:10.1016/j.jaad.2014.06.026PubMedGoogle ScholarCrossref
2.
Loens  K, Ieven  M.  Mycoplasma pneumoniae: current knowledge on nucleic acid amplification techniques and serological diagnostics.  Front Microbiol. 2016;7:448. doi:10.3389/fmicb.2016.00448PubMedGoogle ScholarCrossref
3.
Canadian Agency for Drugs and Technologies in Health.  Serum IgM and Molecular Tests for Mycoplasma pneumoniae Detection: A Review of Diagnostic Test Accuracy, Clinical Effectiveness, Cost-Effectiveness, and Guidelines. Ottawa, ON: Canadian Agency for Drugs and Technologies in Health; 2015.
4.
Lee  SC, Youn  YS, Rhim  JW, Kang  JH, Lee  KY.  Early serologic diagnosis of Mycoplasma pneumoniae pneumonia: an observational study on changes in titers of specific IgM antibodies and cold agglutinins.  Medicine (Baltimore). 2016;95(19):e3605. doi:10.1097/MD.0000000000003605PubMedGoogle ScholarCrossref
5.
Lee  WJ, Huang  EY, Tsai  CM,  et al.  Role of serum Mycoplasma pneumoniae IgA, IgM, and IgG in the diagnosis of Mycoplasma pneumoniae–related pneumonia in school-age children and adolescents.  Clin Vaccine Immunol. 2017;24(1):e00471-e16. doi:10.1128/CVI.00471-16PubMedGoogle ScholarCrossref
6.
Sillis  M.  The limitations of IgM assays in the serological diagnosis of Mycoplasma pneumoniae infections.  J Med Microbiol. 1990;33(4):253-258. doi:10.1099/00222615-33-4-253PubMedGoogle ScholarCrossref
7.
Pereyre  S, Goret  J, Bébéar  C.  Mycoplasma pneumoniae: current knowledge on macrolide resistance and treatment.  Front Microbiol. 2016;7:974. doi:10.3389/fmicb.2016.00974PubMedGoogle ScholarCrossref
8.
Taylor-Robinson  D, Bébéar  C.  Antibiotic susceptibilities of mycoplasmas and treatment of mycoplasmal infections.  J Antimicrob Chemother. 1997;40(5):622-630. doi:10.1093/jac/40.5.622PubMedGoogle ScholarCrossref
9.
Martire  B, Foti  C, Cassano  N, Buquicchio  R, Del Vecchio  GC, De Mattia  D.  Persistent B-cell lymphopenia, multiorgan disease, and erythema multiforme caused by Mycoplasma pneumoniae infection.  Pediatr Dermatol. 2005;22(6):558-560. doi:10.1111/j.1525-1470.2005.00140.xPubMedGoogle ScholarCrossref
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