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A Woman With Dyspnea and Bronchiectasis

Educational Objective
Based on this clinical scenario and the accompanying image, understand how to arrive at a correct diagnosis.
1 Credit CME

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Article Information

Correction: This article was corrected on October 8, 2019, for an incorrect drug class in the text.

Corresponding Author: Ali Ataya, MD, Division of Pulmonary, Critical Care and Sleep Medicine, University of Florida, 1600 SW Archer Rd, M452, Gainesville, FL 32610 (AliAtaya@gmail.com).

Published Online: July 5, 2019. doi:10.1001/jama.2019.8606

Conflict of Interest Disclosures: None reported.

Additional Contributions: We thank the patient for providing permission to share her information.

References
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Soriano  JB, Abajobir  AA, Abate  KH,  et al; GBD 2015 Chronic Respiratory Disease Collaborators.  Global, regional, and national deaths, prevalence, disability-adjusted life years, and years lived with disability for chronic obstructive pulmonary disease and asthma, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015.  Lancet Respir Med. 2017;5(9):691-706. doi:10.1016/S2213-2600(17)30293-XPubMedGoogle ScholarCrossref
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McElvaney  NG, Stoller  JK, Buist  AS,  et al; α1-Antitrypsin Deficiency Registry Study Group.  Baseline characteristics of enrollees in the National Heart, Lung and Blood Institute Registry of α1-antitrypsin deficiency.  Chest. 1997;111(2):394-403. doi:10.1378/chest.111.2.394PubMedGoogle ScholarCrossref
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Parr  DG, Guest  PG, Reynolds  JH, Dowson  LJ, Stockley  RA.  Prevalence and impact of bronchiectasis in α1-antitrypsin deficiency.  Am J Respir Crit Care Med. 2007;176(12):1215-1221. doi:10.1164/rccm.200703-489OCPubMedGoogle ScholarCrossref
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Vogelmeier  CF, Criner  GJ, Martinez  FJ,  et al.  Global strategy for the diagnosis, management, and prevention of chronic obstructive lung disease 2017 report: GOLD executive summary.  Am J Respir Crit Care Med. 2017;195(5):557-582. doi:10.1164/rccm.201701-0218PPPubMedGoogle ScholarCrossref
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