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Bladder pain syndrome (BPS) is a common chronic pelvic pain condition that affects an estimated 7.9 million women in the United States.1 Although the nomenclature for BPS remains controversial, the American Urological Association defines BPS/interstitial cystitis as “an unpleasant sensation (pain, pressure, discomfort) perceived to be related to the urinary bladder, associated with lower urinary tract symptoms of more than six weeks duration, in the absence of infection or other identifiable causes.”1 Patients may present to several different clinicians and describe “flares” of worsening symptoms triggered by stress, intercourse, menses, or diet.
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Corresponding Author: Larissa Bresler, MD, Department of Urology, Stritch School of Medicine, Loyola University Chicago, 2160 S First Ave, Maywood, IL 60153 (firstname.lastname@example.org).
Published Online: November 22, 2019. doi:10.1001/jama.2019.16927
Conflict of Interest Disclosures: Dr Bresler reported receipt of grants from the Interstitial Cystitis Association. Dr Fitzgerald reported receiving personal fees from UpToDate; Loyola University Chicago; Loyola Medical Center; Blasingame, Burch, Garrard, & Ashley PC; PainWeek; Springer; Salvi, Schostok, & Pritchard PC; and Wagstaff & Cartmell LLP; receiving grants from the National Institutes of Health; serving as president of the International Pelvic Pain Society; and holding a device patent (no royalties received). No other disclosures were reported.
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