Eosinophilic esophagitis (EoE)
C. Prescribe omeprazole (40 mg twice daily)
The key to the correct diagnosis is the esophageal mucosal biopsies demonstrating numerous intraepithelial eosinophils, in the setting of dysphagia symptoms and supportive endoscopic findings, and the absence of alternate etiologies for the eosinophilia.1 Other etiologies of esophageal eosinophilia, such as gastroesophageal reflux disease, eosinophilic gastroenteritis, hypereosinophilic syndrome, infections, drug hypersensitivity reaction, Crohn disease, or achalasia, should be carefully considered and excluded based on presenting history, physical examination findings, and diagnostic data.1 Once the diagnosis of EoE was made, the patient was prescribed twice-daily proton pump inhibitor (PPI) therapy, a well-tolerated first-line treatment option.