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Infection Control

Presumed Asymptomatic Carrier Transmission of COVID-19

Educational Objective
Understand the transmission rates of asymptomatic carriers of COVID-19

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JAMA

April 14, 2020

Research Letter

Article Information and Disclosures

Meiyun Wang, MD, PhD¹

Author Affiliations

¹Department of Medical Imaging, Henan Provincial People’s Hospital, Zhengzhou, Henan, China
²Department of Radiology, Anyang Hospital of Traditional Chinese Medicine, Anyang, Henan, China
³Department of Radiology and Interventional, the Fifth People's Hospital of Anyang, Anyang, Henan, China
⁴Tianjin Medical University Cancer Institute and Hospital, Tianjin, China
⁵Li Ka Shing Faculty of Medicine, the University of Hong Kong, Pokfulam, Hong Kong, China

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Article Information

Corresponding Author: Meiyun Wang, MD, PhD, Department of Medical Imaging, Henan Provincial People’s Hospital and the People’s Hospital of Zhengzhou University, No. 7, WeiWu Road, Zhengzhou 450003, Henan, China (mywang@ha.edu.cn).

Published Online: February 21, 2020. doi:10.1001/jama.2020.2565

Author Contributions: Drs Yao and Wang had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis. Drs Bai, Yao, and Wei contributed equally to the work.

Concept and design: Bai, Yao, Tian, Jin, Wang.

Acquisition, analysis, or interpretation of data: Bai, Yao, Wei, Tian, Chen, Wang.

Drafting of the manuscript: Bai, Yao, Wei, Tian, Wang.

Critical revision of the manuscript for important intellectual content: Bai, Tian, Jin, Chen, Wang.

Statistical analysis: Bai, Chen, Wang.

Administrative, technical, or material support: Bai, Yao, Wei, Tian, Wang.

Supervision: Tian, Wang.

Conflict of Interest Disclosures: None reported.

Additional Contributions: We thank Taiyuan Liu, MD, Rushi Chen, MD, and Wei Wei, MD (Henan Provincial People’s Hospital and the People’s Hospital of Zhengzhou University), for data analysis and literature research. None of these persons received any compensation for their contributions.

References

Paules CI , Marston HD , Fauci AS . Coronavirus infections—more than just the common cold. JAMA. Published online January 23, 2020. doi:10.1001/jama.2020.0757 PubMed Google Scholar

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Wang D , Hu B , Hu C , et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus–infected pneumonia in Wuhan, China. JAMA. Published online February 7, 2020. doi:10.1001/jama.2020.1585 PubMed Google Scholar

Guan WJ , Ni ZY , Hu Y , et al. Clinical characteristics of 2019 novel coronavirus infection in China. medRxiv. Published February 9, 2020. Accessed February 18, 2020. https://www.medrxiv.org/content/10.1101/2020.02.06.20020974v1

Corman VM , Landt O , Kaiser M , et al. Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR. Euro Surveill. Published online January 23, 2020. doi:10.2807/1560-7917.ES.2020.25.3.2000045 PubMed Google Scholar

Chan JF , Yuan S , Kok KH , et al. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster. Lancet. 2020;395(10223):514-523. doi:10.1016/S0140-6736(20)30154-9 PubMed Google Scholar Crossref

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