[Skip to Content]
[Skip to Content Landing]

An Acute Respiratory Infection Runs Into the Most Common Noncommunicable Epidemic—COVID-19 and Cardiovascular Diseases

Educational Objective
Review the impact of COVID-19 on patients with comorbid CVDs
1 Credit CME

The outbreak of novel coronavirus disease 2019 (COVID-19), which emerged in Wuhan, China, in December 2019, has rapidly spread to more than 58 countries and areas.1 As of March 1, 2020, about 79 968 cases in mainland China have been confirmed and 2873 deaths have occurred.1 The Chinese government is mustering medical personnel around the country to treat patients in Hubei province and preventing further spread of COVID-19 in every region of the country.

Sign in to take quiz and track your certificates

Buy This Activity

JN Learning™ is the home for CME and MOC from the JAMA Network. Search by specialty or US state and earn AMA PRA Category 1 CME Credit™ from articles, audio, Clinical Challenges and more. Learn more about CME/MOC

Article Information

Corresponding Authors: Zening Jin, MD, PhD (jin_zening@163.com), and Chengzhi Yang, MD, PhD (yangcz@hsc.pku.edu.cn), Department of Cardiology and Macrovascular Disease, Beijing Tiantan Hospital, No. 119 South Fourth Ring West Rd, Beijing 100070, China.

Published Online: March 25, 2020. doi:10.1001/jamacardio.2020.0934

Conflict of Interest Disclosures: None reported.

Funding/Support: This work was supported by the National Natural Science Foundation of China (grant 81900452).

Role of the Funder/Sponsor: The funder had no role in the preparation, review, or approval of the manuscript and decision to submit the manuscript for publication.

References
1.
World Health Organization. Coronavirus disease 2019 (COVID-19) situation report–41. Published March 1, 2020. Accessed February 29, 2020. https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200301-sitrep-41-covid-19.pdf?sfvrsn=6768306d_2
2.
Novel Coronavirus Pneumonia Emergency Response Epidemiology Team.  The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) in China.  Zhonghua Liu Xing Bing Xue Za Zhi. Article published in Chinese. 2020;41(2):145-151.PubMedGoogle Scholar
3.
Wang  D, Hu  B, Hu  C,  et al.  Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China  .  JAMA. Published online February 7, 2020. doi:10.1001/jama.2020.1585PubMedGoogle Scholar
4.
Huang  C, Wang  Y, Li  X,  et al.  Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China.  Lancet. 2020;395(10223):497-506. doi:10.1016/S0140-6736(20)30183-5PubMedGoogle ScholarCrossref
5.
Chen  N, Zhou  M, Dong  X,  et al.  Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study.  Lancet. 2020;395(10223):507-513. doi:10.1016/S0140-6736(20)30211-7PubMedGoogle ScholarCrossref
6.
Wrapp  D, Wang  N, Corbett  KS,  et al.  Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation.  Science. 2020;b2507. doi:10.1126/science.abb2507PubMedGoogle Scholar
7.
Yu  CM, Wong  RS, Wu  EB,  et al.  Cardiovascular complications of severe acute respiratory syndrome.  Postgrad Med J. 2006;82(964):140-144. doi:10.1136/pgmj.2005.037515PubMedGoogle ScholarCrossref
8.
Xu  Z, Shi  L, Wang  Y,  et al.  Pathological findings of COVID-19 associated with acute respiratory distress syndrome.  Lancet Respir Med. 2020;S2213-2600(20)30076-X. doi:10.1016/S2213-2600(20)30076-XPubMedGoogle Scholar
9.
Li  SS, Cheng  CW, Fu  CL,  et al.  Left ventricular performance in patients with severe acute respiratory syndrome.  Circulation. 2003;108(15):1798-1803. doi:10.1161/01.CIR.0000094737.21775.32PubMedGoogle ScholarCrossref
10.
Patel  VB, Zhong  JC, Grant  MB, Oudit  GY.  Role of the ACE2/angiotensin 1-7 axis of the renin-angiotensin system in heart failure.  Circ Res. 2016;118(8):1313-1326. doi:10.1161/CIRCRESAHA.116.307708PubMedGoogle ScholarCrossref
If you are not a JN Learning subscriber, you can either:
Subscribe to JN Learning for one year
Buy this activity
jn-learning_Modal_LoginSubscribe_Purchase
Close
If you are not a JN Learning subscriber, you can either:
Subscribe to JN Learning for one year
Buy this activity
jn-learning_Modal_LoginSubscribe_Purchase
Close
With a personal account, you can:
  • Access free activities and track your credits
  • Personalize content alerts
  • Customize your interests
  • Fully personalize your learning experience
Education Center Collection Sign In Modal Right
Close

Name Your Search

Save Search
Close
With a personal account, you can:
  • Track your credits
  • Personalize content alerts
  • Customize your interests
  • Fully personalize your learning experience
jn-learning_Modal_SaveSearch_NoAccess_Purchase
Close

Lookup An Activity

or

Close

My Saved Searches

You currently have no searches saved.

Close
With a personal account, you can:
  • Access free activities and track your credits
  • Personalize content alerts
  • Customize your interests
  • Fully personalize your learning experience
Education Center Collection Sign In Modal Right
Close