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An Acute Respiratory Infection Runs Into the Most Common Noncommunicable Epidemic—COVID-19 and Cardiovascular Diseases

Educational Objective
Review the impact of COVID-19 on patients with comorbid CVDs
1 Credit CME

The outbreak of novel coronavirus disease 2019 (COVID-19), which emerged in Wuhan, China, in December 2019, has rapidly spread to more than 58 countries and areas.1 As of March 1, 2020, about 79 968 cases in mainland China have been confirmed and 2873 deaths have occurred.1 The Chinese government is mustering medical personnel around the country to treat patients in Hubei province and preventing further spread of COVID-19 in every region of the country.

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Article Information

Corresponding Authors: Zening Jin, MD, PhD (jin_zening@163.com), and Chengzhi Yang, MD, PhD (yangcz@hsc.pku.edu.cn), Department of Cardiology and Macrovascular Disease, Beijing Tiantan Hospital, No. 119 South Fourth Ring West Rd, Beijing 100070, China.

Published Online: March 25, 2020. doi:10.1001/jamacardio.2020.0934

Conflict of Interest Disclosures: None reported.

Funding/Support: This work was supported by the National Natural Science Foundation of China (grant 81900452).

Role of the Funder/Sponsor: The funder had no role in the preparation, review, or approval of the manuscript and decision to submit the manuscript for publication.

References
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World Health Organization. Coronavirus disease 2019 (COVID-19) situation report–41. Published March 1, 2020. Accessed February 29, 2020. https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200301-sitrep-41-covid-19.pdf?sfvrsn=6768306d_2
2.
Novel Coronavirus Pneumonia Emergency Response Epidemiology Team.  The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) in China.   Zhonghua Liu Xing Bing Xue Za Zhi. Article published in Chinese. 2020;41(2):145-151.PubMedGoogle Scholar
3.
Wang  D , Hu  B , Hu  C ,  et al.  Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China  .  JAMA. Published online February 7, 2020. doi:10.1001/jama.2020.1585 PubMedGoogle Scholar
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Huang  C , Wang  Y , Li  X ,  et al.  Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China.   Lancet. 2020;395(10223):497-506. doi:10.1016/S0140-6736(20)30183-5 PubMedGoogle ScholarCrossref
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Chen  N , Zhou  M , Dong  X ,  et al.  Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study.   Lancet. 2020;395(10223):507-513. doi:10.1016/S0140-6736(20)30211-7 PubMedGoogle ScholarCrossref
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Wrapp  D , Wang  N , Corbett  KS ,  et al.  Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation.   Science. 2020;b2507. doi:10.1126/science.abb2507 PubMedGoogle Scholar
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Yu  CM , Wong  RS , Wu  EB ,  et al.  Cardiovascular complications of severe acute respiratory syndrome.   Postgrad Med J. 2006;82(964):140-144. doi:10.1136/pgmj.2005.037515 PubMedGoogle ScholarCrossref
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Xu  Z , Shi  L , Wang  Y ,  et al.  Pathological findings of COVID-19 associated with acute respiratory distress syndrome.   Lancet Respir Med. 2020;S2213-2600(20)30076-X. doi:10.1016/S2213-2600(20)30076-X PubMedGoogle Scholar
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Li  SS , Cheng  CW , Fu  CL ,  et al.  Left ventricular performance in patients with severe acute respiratory syndrome.   Circulation. 2003;108(15):1798-1803. doi:10.1161/01.CIR.0000094737.21775.32 PubMedGoogle ScholarCrossref
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Patel  VB , Zhong  JC , Grant  MB , Oudit  GY .  Role of the ACE2/angiotensin 1-7 axis of the renin-angiotensin system in heart failure.   Circ Res. 2016;118(8):1313-1326. doi:10.1161/CIRCRESAHA.116.307708 PubMedGoogle ScholarCrossref
AMA CME Accreditation Information

Credit Designation Statement: The American Medical Association designates this Journal-based CME activity activity for a maximum of 1.00  AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to:

  • 1.00 Medical Knowledge MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program;;
  • 1.00 Self-Assessment points in the American Board of Otolaryngology – Head and Neck Surgery’s (ABOHNS) Continuing Certification program;
  • 1.00 MOC points in the American Board of Pediatrics’ (ABP) Maintenance of Certification (MOC) program;
  • 1.00 Lifelong Learning points in the American Board of Pathology’s (ABPath) Continuing Certification program; and
  • 1.00 CME points in the American Board of Surgery’s (ABS) Continuing Certification program

It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting MOC credit.

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