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Since December 2019, an epidemic of coronavirus disease 2019 (COVID-19) has spread rapidly from Wuhan, Hubei Province, China.1 As of March 7, there were 1272 confirmed coronavirus cases in Henan Province (the third-highest in China), which adjoins Hubei Province. Due to the high contagiousness of COVID-19 and the current lack of any effective vaccine or drug, scientists and physicians are conducting a series of clinical studies involving affected patients. In 2016, the World Health Organization (WHO) published “Guidance for Managing Ethical Issues in Infectious Disease”2 to ensure the scientific validity of and participants’ rights and safety in studies conducted during outbreaks. The guidance stated that there is a moral obligation to conduct timely scientific research. The Ethics Committee of the Henan Provincial People’s Hospital reviewed the COVID-19 studies from the hospital based on those guidelines.
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Corresponding Author: Yuming Wang, MD, PhD, Henan Provincial People’s Hospital and the People’s Hospital of Zhengzhou University, No. 7, Weiwu Rd, Zhengzhou 450003, Henan, China (email@example.com).
Published Online: March 23, 2020. doi:10.1001/jama.2020.4362
Author Contributions: Dr Wang and Ms Zhang had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.
Concept and design: Shao, Gu, Li, Wang.
Acquisition, analysis, or interpretation of data: Zhang, Wang.
Drafting of the manuscript: Zhang, Wang.
Critical revision of the manuscript for important intellectual content: Shao, Gu, Li, Wang.
Statistical analysis: Zhang, Wang.Administrative, technical, or material support: Shao, Gu, Li, Wang.Supervision: Shao, Gu, Wang.
Conflict of Interest Disclosures: None reported.
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