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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is highly infectious, with multiple possible routes of transmission.1- 3 Controversy exists regarding whether SARS-CoV-2 can be transmitted in utero from an infected mother to her infant before birth. A series of 9 pregnant women found no mother-child transmission.4 We report a newborn with elevated IgM antibodies to SARS-CoV-2 born to a mother with coronavirus disease 2019 (COVID-19).
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Corresponding Authors: Jing Yang, MD, Department of Obstetrics & Gynecology, Renmin Hospital of Wuhan University, 283 Jiefang Rd, Wuhan, Hubei 430060, China (firstname.lastname@example.org); Chen Liu, MD, Department of Radiology, First Affiliated Hospital to Army Medical University, 30 Gao Tan Yan St, Chongqing 400038, China (email@example.com).
Published Online: March 26, 2020. doi:10.1001/jama.2020.4621
Author Contributions: Drs Liu and Yang had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis. Drs Dong and Tian contributed equally to the study. Drs Liu and Yang contributed equally as senior authors.
Concept and design: Wang, Liu, Yang.
Acquisition, analysis, or interpretation of data: Dong, Tian, He, Zhu.
Drafting of the manuscript: Dong, Tian, He, Zhu, Liu.
Critical revision of the manuscript for important intellectual content: Zhu, Wang, Liu, Yang.
Statistical analysis: Dong, Tian, He, Liu.
Obtained funding: Zhu, Wang, Liu, Yang.
Supervision: Zhu, Yang.
Conflict of Interest Disclosures: None reported.
Funding/Support: This work was supported by the Chongqing Key technology and application demonstration of medical imaging depth intelligent diagnostic platform (cstc2018jszx-cyztzxX0017), the National Key Research and Development Project (2018YFC1002804, 2016YFC1000600), and the National Natural Science Foundation of China (No. 81771618 and No. 81801524).
Role of the Funder/Sponsor: The funders had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
Additional Contributions: We thank the family members who were involved in this study and we thank the patient for granting permission to publish this information.
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