Tests for IgG and IgM antibodies for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) became available in February 2020. On March 4, 2020, the seventh edition of the New Coronavirus Pneumonia Prevention and Control Protocol for the novel coronavirus disease 2019 (COVID-19) was released by the National Health Commission of the People’s Republic of China and added serological diagnostic criteria.1 A previous study of 9 pregnant women and their infants found no maternal-infant transmission of SARS-CoV-2 based on reverse transcriptase–polymerase chain reaction (RT-PCR).2 We applied these new criteria to 6 pregnant women with confirmed COVID-19 and their infants because serologic criteria would allow more detailed investigation of infection in newborns.
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CME Disclosure Statement: Unless noted, all individuals in control of content reported no relevant financial relationships. If applicable, all relevant financial relationships have been mitigated.
Corresponding Authors: Xinghua Long, MD, PhD (email@example.com) and Wei Zhang, MD, PhD (firstname.lastname@example.org), Zhongnan Hospital of Wuhan University, 169 Donghu Rd, Wuhan, China.
Published Online: March 26, 2020. doi:10.1001/jama.2020.4861
Author Contributions: Drs Long and Zhang had full access to all the data in the study and take responsibility for the integrity of the data and accuracy of the data analysis. Dr Zeng and Ms Xu contributed equally to the study.
Concept and design: Zeng, Xu, Long.Acquisition, analysis, or interpretation of data: Fan, Tang, Deng, Zhang.Drafting of the manuscript: Zeng, Xu, Long.Critical revision of the manuscript for important intellectual content: Fang, Tang, Deng, Zhang.Statistical analysis: Zeng, Xu, Fan, Tang, Deng.Obtained funding: Long.Supervision: Zhang.
Conflict of Interest Disclosures: None reported.
Funding/Support: This study was supported by grants 81272372 from the National Natural Science Foundation of China and znpy2016033 from Zhongnan Hospital of Wuhan University Science, Technology, and Innovation Seed Fund.
Role of the Funder/Sponsor: The sponsors had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
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