Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of COVID-19, a pandemic that has affected more than 400 000 individuals and caused nearly 20 000 deaths as of late March 2020. Approximately 5% to 10% of patients require intensive care unit (ICU) admission and mechanical ventilation.1
The Surviving Sepsis Campaign (SSC) has previously published a series of guidelines for sepsis and septic shock. Based on this experience, experts were recruited to write guidelines on the management of COVID-19 in critically ill adults. These guidelines were authored by 36 experts from 12 countries (Table).2 Recommendations were developed based on limited direct evidence with COVID-19 cases and indirect evidence derived from previous pandemics such as Middle East respiratory syndrome (MERS), severe acute respiratory syndrome (SARS), and other coronavirus infections. Overall, the panel issued 54 statements: 4 best practice statements, 9 strong recommendations, and 35 weak recommendations. (No recommendations were made for the remaining 6 topics.)
Sign in to take quiz and track your certificates
JN Learning™ is the home for CME and MOC from the JAMA Network. Search by specialty or US state and earn AMA PRA Category 1 Credit(s)™ from articles, audio, Clinical Challenges and more. Learn more about CME/MOC
CME Disclosure Statement: Unless noted, all individuals in control of content reported no relevant financial relationships. If applicable, all relevant financial relationships have been mitigated.
Corresponding Author: Jason T. Poston, MD, University of Chicago, 850 E 58th St, Chicago, IL 60615 (Jason.Poston@uchospitals.edu).
Published Online: March 26, 2020. doi:10.1001/jama.2020.4914
Correction: This article was corrected on April 3, 2020, to include all of the related resources and relevant publications.
Conflict of Interest Disclosures: Dr Patel reports receiving grants from Parker B. Francis Career Development award and from NIH/NHLBI T32 HL007605 Research Training in Respiratory Biology. Dr Poston receiving honoraria for the CHEST Critical Care Board Review Course. Dr Davis reported no disclosures.
You currently have no searches saved.
You currently have no courses saved.