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Community Prevalence of SARS-CoV-2 Among Patients With Influenzalike Illnesses Presenting to a Los Angeles Medical Center in March 2020

Educational Objective
To Understand the prevalence of SARS-CoV-2 among patients presenting with Influenza symptoms
1 Credit CME

Until recently, diagnostic testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (COVID-19), was only available through public health laboratories.13 This limited testing was prioritized for persons who had severe illness or identifiable risk factors, such as travel to an area with ongoing transmission. Thus, the incidence of community transmission by persons with mild illness and without risk factors remains ill-defined.

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Article Information

Corresponding Author: Brad Spellberg, MD, Los Angeles County + University of Southern California Medical Center, 2051 Marengo St, Los Angeles, CA 90033 (bspellberg@dhs.lacounty.gov).

Published Online: March 31, 2020. doi:10.1001/jama.2020.4958

Author Contributions: Dr Spellberg had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.

Concept and design: Spellberg, Haddix, Holtom, Yee, Gounder.

Acquisition, analysis, or interpretation of data: Spellberg, Haddix, Lee, Butler-Wu, Holtom, Gounder.

Drafting of the manuscript: Spellberg, Gounder.

Critical revision of the manuscript for important intellectual content: All authors.

Statistical analysis: Gounder.

Administrative, technical, or material support: All authors.

Supervision: Spellberg, Holtom, Yee, Gounder.

Conflict of Interest Disclosures: None reported.

Additional Contributions: We acknowledge the tireless surveillance efforts of Bessie Hwang, MD, MPH, and Emily Kajita, MS, MPH (both with the Department of Public Health Acute Communicable Disease Control Syndromic Surveillance Unit), and Elizabeth Traub, MPH (with the Department of Public Health Acute Communicable Disease Control Syndromic Respiratory Diseases Unit). None received additional compensation beyond salary.

References
1.
Del Rio  C , Malani  PN .  2019 novel coronavirus—important information for clinicians.   JAMA. 2020;323(11):1039-1040. doi:10.1001/jama.2020.1490PubMedGoogle ScholarCrossref
2.
Del Rio  C , Malani  PN .  COVID-19—new insights on a rapidly changing epidemic.   JAMA. Published online February 28, 2020. doi:10.1001/jama.2020.3072PubMedGoogle Scholar
3.
Paules  CI , Marston  HD , Fauci  AS .  Coronavirus infections—more than just the common cold.   JAMA. 2020;323(8):707-708. doi:10.1001/jama.2020.0757PubMedGoogle ScholarCrossref
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