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Incorporating Test Characteristics Into SARS-CoV-2 Testing Policy—Sense and Sensitivity

Educational Objective
To understand how to use test characteristics to understand the full scope of COVID-19
1 Credit CME

Amid the ongoing coronavirus disease 2019 (COVID-19) pandemic, the issue of diagnostic testing has been front and center.1 Testing capacity has been woefully insufficient for clinical testing of high-risk individuals, much less for epidemiologic evaluation of prevalence, community spread, and the consequences of public health interventions, such as social and physical distancing, school closures, and geographic shutdowns. We need more testing capacity.

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Article Information

Corresponding Author: Leah M. Marcotte, MD, Department of Medicine, University of Washington, 1959 Pacific St, Seattle, WA 98105 (leahmar@uw.edu).

Conflict of Interest Disclosures: Dr Marcotte reported receiving personal fees from the University of Missouri–Kansas City School of Medicine outside the submitted work. Dr. Liao reported receiving personal fees from Kaiser Permanente Washington Research Institute and textbook royalties and an honorarium from Wolters Kluwer outside the submitted work.

References
1.
Sharfstein  JM , Becker  SJ , Mello  MM .  Diagnostic testing for the novel coronavirus.   JAMA. 2020. Published March 9, 2020. doi:10.1001/jama.2020.3864PubMedGoogle Scholar
2.
Wang  W , Xu  Y , Gao  R ,  et al.  Detection of SARS-CoV-2 in different types of clinical specimens.   JAMA. 2020. Published March 11, 2020. doi:10.1001/jama.2020.3786PubMedGoogle Scholar
3.
Yang  Y , Yang  M , Shen  C ,  et al. Evaluating the accuracy of different respiratory specimens in the laboratory diagnosis and monitoring the viral shedding of 2019-nCoV infections. Accessed April 8, 2020. https://www.medrxiv.org/content/10.1101/2020.02.11.20021493v2
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