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The complex decisions facing clinical teams caring for patients who are critically ill with coronavirus disease 2019 (COVID-19) are compounded by the absence of proven treatment strategies. Lacking robust trial evidence, clinicians are forced to consider all options based on preclinical and small observational studies, often in heart-wrenching settings of patients who are deteriorating in the throes of severe pneumonia, acute respiratory distress syndrome, cytokine storm, and in many cases, cardiovascular complications.
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JN Learning™ is the home for CME and MOC from the JAMA Network. Search by specialty or US state and earn AMA PRA Category 1 CME Credit™ from articles, audio, Clinical Challenges and more. Learn more about CME/MOC
CME Disclosure Statement: Unless noted, all individuals in control of content reported no relevant financial relationships. If applicable, all relevant financial relationships have been mitigated.
Corresponding Author: Robert O. Bonow, MD, MS, Northwestern University Feinberg School of Medicine, 676 N St Clair St, Ste 600, Chicago, IL 60611 (firstname.lastname@example.org).
Published Online: May 1, 2020. doi:10.1001/jamacardio.2020.1782
Conflict of Interest Disclosures: Dr Hernandez reported receiving funds from the Patient-Centered Outcome Research Institute for a clinical trial of hydroxychloroquine to evaluate the efficacy of preexposure prophylaxis among health care workers. Dr Turakhia reported grants from Apple Inc and the American Heart Association and other support from AliveCor outside the submitted work. No other disclosures were reported.
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