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Coronavirus (COVID-19)

COVID-19 in Children With Cancer in New York City

Educational Objective
To understand how COVID-19 is affecting Children with Cancer in New York City.

1 Credit CME

JAMA Oncology

Published Online: May 13, 2020

Research Letter

Article Information and Disclosures

Farid Boulad, MD¹;

Mini Kamboj, MD²;

Nancy Bouvier, BA¹;

Audrey Mauguen, PhD³;

Andrew L. Kung, MD, PhD¹

Author Affiliations

¹Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York
²Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York
³Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York

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Data on the prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in children,¹^- 4 and in children with cancer specifically have been limited. Less than 1% of cases reported from China were in children younger than 10 years.³ The MSK Kids pediatric program at Memorial Sloan Kettering Cancer Center (MSK) is one of the largest pediatric cancer programs in the US. Starting in mid-March, 2020, we instituted a screening and testing plan to mitigate risk associated with coronavirus disease 2019 (COVID-19).

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Article Information

Corresponding Author: Andrew L. Kung, MD, PhD, Department of Pediatrics, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10065 (kunga@mskcc.org).

Accepted for Publication: April 27, 2020.

Published Online: May 13, 2020. doi:10.1001/jamaoncol.2020.2028

Author Contributions: Drs Boulad and Kung had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.

Concept and design: Boulad, Kung.

Acquisition, analysis, or interpretation of data: All authors.

Drafting of the manuscript: Boulad, Kung.

Critical revision of the manuscript for important intellectual content: All authors.

Statistical analysis: Mauguen, Kung.

Administrative, technical, or material support: Bouvier, Kung.

Supervision: Kamboj, Kung.

Funding/Support: These studies were supported by internal institutional funding from the Memorial Sloan Kettering Cancer Center.

Role of the Funder/Sponsor: The Memorial Sloan Kettering Cancer Center had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.

Additional Contributions: We thank the healthcare providers who conducted the SARS-CoV-2 testing and responded to COVID-19 illness described in this report.

References

Zhu N , Zhang D , Wang W , et al; China Novel Coronavirus Investigating and Research Team. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020;382(8):727-733. doi:10.1056/NEJMoa2001017 PubMed Google Scholar Crossref

Qiu H , Wu J , Hong L , Luo Y , Song Q , Chen D . Clinical and epidemiological features of 36 children with coronavirus disease 2019 (COVID-19) in Zhejiang, China: an observational cohort study. Lancet Infect Dis. 2020;S1473-3099(20)30198-5. doi:10.1016/S1473-3099(20)30198-5 PubMed Google Scholar

Lu X , Zhang L , Du H , et al; Chinese Pediatric Novel Coronavirus Study Team. SARS-CoV-2 infection in children. N Engl J Med. 2020;382(17):1663-1665. doi:10.1056/NEJMc2005073 PubMed Google Scholar Crossref

Choi SH , Kim HW , Kang JM , Kim DH , Cho EY . Epidemiology and clinical features of coronavirus disease 2019 in children. Clin Exp Pediatr. 2020;63(4):125-132. doi:10.3345/cep.2020.00535 PubMed Google Scholar Crossref

Grasselli G , Zangrillo A , Zanella A , et al; COVID-19 Lombardy ICU Network. Baseline characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the Lombardy Region, Italy. JAMA. 2020.PubMed Google Scholar

Sutton D , Fuchs K , D’Alton M , Goffman D . Universal screening for SARS-CoV-2 in women admitted for delivery. N Engl J Med. 2020. doi:10.1056/NEJMc2009316 PubMed Google Scholar

AMA CME Accreditation Information

Credit Designation Statement: The American Medical Association designates this Journal-based CME activity activity for a maximum of 1.00  AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to:

1.00 Medical Knowledge MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program;;
1.00 Self-Assessment points in the American Board of Otolaryngology – Head and Neck Surgery’s (ABOHNS) Continuing Certification program;
1.00 MOC points in the American Board of Pediatrics’ (ABP) Maintenance of Certification (MOC) program;
1.00 Lifelong Learning points in the American Board of Pathology’s (ABPath) Continuing Certification program; and
1.00 CME points in the American Board of Surgery’s (ABS) Continuing Certification program

It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting MOC credit.