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COVID-19 in Children With Cancer in New York City

Educational Objective
To understand how COVID-19 is affecting Children with Cancer in New York City.
1 Credit CME

Data on the prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in children,14 and in children with cancer specifically have been limited. Less than 1% of cases reported from China were in children younger than 10 years.3 The MSK Kids pediatric program at Memorial Sloan Kettering Cancer Center (MSK) is one of the largest pediatric cancer programs in the US. Starting in mid-March, 2020, we instituted a screening and testing plan to mitigate risk associated with coronavirus disease 2019 (COVID-19).

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Article Information

Corresponding Author: Andrew L. Kung, MD, PhD, Department of Pediatrics, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10065 (kunga@mskcc.org).

Accepted for Publication: April 27, 2020.

Published Online: May 13, 2020. doi:10.1001/jamaoncol.2020.2028

Author Contributions: Drs Boulad and Kung had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.

Concept and design: Boulad, Kung.

Acquisition, analysis, or interpretation of data: All authors.

Drafting of the manuscript: Boulad, Kung.

Critical revision of the manuscript for important intellectual content: All authors.

Statistical analysis: Mauguen, Kung.

Administrative, technical, or material support: Bouvier, Kung.

Supervision: Kamboj, Kung.

Funding/Support: These studies were supported by internal institutional funding from the Memorial Sloan Kettering Cancer Center.

Role of the Funder/Sponsor: The Memorial Sloan Kettering Cancer Center had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.

Additional Contributions: We thank the healthcare providers who conducted the SARS-CoV-2 testing and responded to COVID-19 illness described in this report.

References
1.
Zhu  N , Zhang  D , Wang  W ,  et al; China Novel Coronavirus Investigating and Research Team.  A novel coronavirus from patients with pneumonia in China, 2019.   N Engl J Med. 2020;382(8):727-733. doi:10.1056/NEJMoa2001017PubMedGoogle ScholarCrossref
2.
Qiu  H , Wu  J , Hong  L , Luo  Y , Song  Q , Chen  D .  Clinical and epidemiological features of 36 children with coronavirus disease 2019 (COVID-19) in Zhejiang, China: an observational cohort study.   Lancet Infect Dis. 2020;S1473-3099(20)30198-5. doi:10.1016/S1473-3099(20)30198-5PubMedGoogle Scholar
3.
Lu  X , Zhang  L , Du  H ,  et al; Chinese Pediatric Novel Coronavirus Study Team.  SARS-CoV-2 infection in children.   N Engl J Med. 2020;382(17):1663-1665. doi:10.1056/NEJMc2005073PubMedGoogle ScholarCrossref
4.
Choi  SH , Kim  HW , Kang  JM , Kim  DH , Cho  EY .  Epidemiology and clinical features of coronavirus disease 2019 in children.   Clin Exp Pediatr. 2020;63(4):125-132. doi:10.3345/cep.2020.00535PubMedGoogle ScholarCrossref
5.
Grasselli  G , Zangrillo  A , Zanella  A ,  et al; COVID-19 Lombardy ICU Network.  Baseline characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the Lombardy Region, Italy.   JAMA. 2020.PubMedGoogle Scholar
6.
Sutton  D , Fuchs  K , D’Alton  M , Goffman  D .  Universal screening for SARS-CoV-2 in women admitted for delivery.   N Engl J Med. 2020. doi:10.1056/NEJMc2009316PubMedGoogle Scholar
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