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Infectious Diseases

Coronavirus Disease 2019 Test Results After Clinical Recovery and Hospital Discharge Among Patients in China

Educational Objective
To understand the importance of assessing the COVID-19 infected patient’s health and recovery period after being discharged

1 Credit CME

JAMA Network Open

Published Online: May 22, 2020

Research Letter

Article Information and Disclosures

Jinru Wu, BS^1,2;

Xinyi Liu, BS¹;

Jianjun Liu, BS²;

Han Liao, BS³;

Sixuan Long, BS²;

Ning Zhou, MD, PhD⁴;

Author Affiliations

¹College of Life Science, Hunan Normal University, Changsha, China
²Loudi Center for Disease Control and Prevention, Loudi, China
³Louxing District Center for Disease Control and Prevention, Loudi, China
⁴Department of Infectious Diseases, the Second Xiangya Hospital, Central South University, Changsha, China

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Article Information

Accepted for Publication: April 25, 2020.

Published: May 22, 2020. doi:10.1001/jamanetworkopen.2020.9759

Open Access: This is an open access article distributed under the terms of the CC-BY License. © 2020 Wu J et al. JAMA Network Open.

Corresponding Author: Pa Wu, PhD, College of Life Science, Hunan Normal University, No. 36, Lushan South Rd., Changsha 410081, China (wupa@hunnu.edu.cn).

Author Contributions: Mr J. Wu and Dr P. Wu had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.

Concept and design: J. Wu, P. Wu.

Acquisition, analysis, or interpretation of data: All authors.

Drafting of the manuscript: J. Wu, P. Wu.

Critical revision of the manuscript for important intellectual content: All authors.

Statistical analysis: J. Wu, X. Liu, P. Wu.

Obtained funding: P. Wu.

Administrative, technical, or material support: Zhou.

Supervision: J. Wu, P. Wu.

Conflict of Interest Disclosures: None reported.

Funding/Support: This work was supported by grants No. 81902094 and 81600497 from the National Natural Science Foundation of China (Dr Zhou) and grant No. 2019RS1036 from the Science and Technology Plan Project of Hunan Province (Dr P. Wu).

Role of the Funder/Sponsor: The funders had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.

References

Chan JF , Yuan S , Kok KH , et al. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster. Lancet. 2020;395(10223):514-523. doi:10.1016/S0140-6736(20)30154-9 PubMed Google Scholar Crossref

Lan L , Xu D , Ye G , et al. Positive RT-PCR test results in patients recovered from COVID-19. JAMA. 2020;323(15):1502-1503. doi:10.1001/jama.2020.2783 PubMed Google Scholar Crossref

China National Health Commission. Diagnosis and treatment of 2019-nCoV pneumonia in China [in Chinese]. Published February 18, 2020. Accessed April 28, 2020. http://www.nhc.gov.cn/yzygj/s7653p/202002/8334a8326dd94d329df351d7da8aefc2/files/b218cfeb1bc54639af227f922bf6b817.pdf

Xing Y-H , Ni W , Wu Q , et al. Prolonged viral shedding in feces of pediatric patients with coronavirus disease 2019. J Microbiol Immunol Infect. 2020;1182(1620):30081-30085. doi:10.1016/j.jmii.2020.03.021 PubMed Google Scholar

Wölfel R , Corman VM , Guggemos W , et al. Virological assessment of hospitalized patients with COVID-2019. Nature. Published online April 1, 2020. doi:10.1038/s41586-020-2196-x PubMed Google Scholar

AMA CME Accreditation Information

Credit Designation Statement: The American Medical Association designates this Journal-based CME activity activity for a maximum of 1.00  AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to:

1.00 Medical Knowledge MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program;;
1.00 Self-Assessment points in the American Board of Otolaryngology – Head and Neck Surgery’s (ABOHNS) Continuing Certification program;
1.00 MOC points in the American Board of Pediatrics’ (ABP) Maintenance of Certification (MOC) program;
1.00 Lifelong Learning points in the American Board of Pathology’s (ABPath) Continuing Certification program; and
1.00 CME points in the American Board of Surgery’s (ABS) Continuing Certification program

It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting MOC credit.