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Severe coronavirus disease 2019 (COVID-19) has been reported rarely in children.1,2 International data suggest the development of a proinflammatory syndrome with features of Kawasaki disease (KD) or toxic shock syndrome (TSS) in children, possibly related to COVID-19.3
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Corresponding Author: Eva W. Cheung, MD, Divisions of Cardiology and Critical Care, Department of Pediatrics, Columbia University Irving Medical Center, 3959 Broadway, CHN 2 North, New York, NY 10032 (firstname.lastname@example.org).
Accepted for Publication: May 27, 2020.
Published Online: June 8, 2020. doi:10.1001/jama.2020.10374
Author Contributions: Drs Cheung and Zachariah had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis. Drs Cheung and Zachariah contributed equally to the authorship of this article.
Concept and design: All authors.
Acquisition, analysis, or interpretation of data: Cheung, Zachariah, Gorelik, Boneparth, Orange, Milner.
Drafting of the manuscript: Cheung, Zachariah, Gorelik, Boneparth, Milner.
Critical revision of the manuscript for important intellectual content: All authors.
Statistical analysis: Cheung, Zachariah.
Administrative, technical, or material support: Zachariah, Gorelik, Orange.
Supervision: Kernie, Orange, Milner.
Conflict of Interest Disclosures: Dr Orange reported receiving personal fees from ADMA Biologics, CSL Bhering, Gigagen, Grifols, and Takeda. No other disclosures were reported.
Additional Contributions: Candace Johnson, MD, Kara Gross-Margolis, MD, Irene Lytrivi, MD, Angela Chan, MD, and Brian Jonat, MD, MPH (Department of Pediatrics, Columbia University Irving Medical Center), contributed to data collection and analysis and editing assistance for this letter. Eldad A. Hod, MD (Department of Pathology and Cell Biology, Columbia University Irving Medical Center), contributed to data collection and writing of the manuscript. None of these individuals were compensated for their contributions.
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