Concerns have been raised about how journals maintain their standards during the current coronavirus disease 2019 (COVID-19) pandemic, given the rapid pace and unprecedented volume of research being conducted in such a short time, and the large number of reports submitted to journals. For example, at JAMA, from January 1 to June 1, 2020, more than 11 000 manuscripts were submitted, compared with approximately 4000 manuscripts submitted during the same period in 2019. Virtually the entire increase has been related to manuscripts focused on COVID-19, with about one-third representing original research (full-length manuscripts, brief reports, and research letters) and two-thirds representing opinion (Viewpoints, A Piece of My Mind) and reviews.