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A safe and effective vaccine against coronavirus disease 2019 (COVID-19) is the best way to control and ultimately end the pandemic. Vaccine development is moving at unprecedented speed, with more than 200 candidates, billions of dollars committed, and manufacturing often proceeding before even knowing whether a given vaccine candidate will succeed. To date, the US federal government has rapidly advanced 5 vaccine candidates through Operation Warp Speed.1 At the same time, a growing movement of skeptics has raised doubt about future COVID-19 vaccines.2 A poll of 1056 individuals in the US found that only 49% reported that they currently are planning to receive a COVID-19 vaccine; 31% are uncertain, and 20% are not, with safety a major concern.3
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CME Disclosure Statement: Unless noted, all individuals in control of content reported no relevant financial relationships. If applicable, all relevant financial relationships have been mitigated.
Corresponding Author: Nicole Lurie, MD, MSPH, Coalition for Epidemic Preparedness Innovations (CEPI), 1900 Pennsylvania Ave NW, Washington, DC 20006 (email@example.com).
Published Online: July 6, 2020. doi:10.1001/jama.2020.12461
Conflict of Interest Disclosures: Dr Sharfstein reported that he served as Principal Deputy Commissioner of FDA from March 2009 to January 2011. Dr Goodman reported that he served as the Chief Scientist of the FDA from January 2009 to March 2014. No other disclosures were reported.
Disclaimer: The views expressed herein are solely those of the authors, and do not necessarily represent the views of any organizations with which they are affiliated.
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