Seroprevalence of Antibodies to SARS-CoV-2 in 10 Sites in the United States, March 23-May 12, 2020

Accepted for Publication: July 7, 2020.

Corresponding Author: Fiona P. Havers, MD, MHS, CDC COVID-19 Response Team, Centers for Disease Control and Prevention, 1600 Clifton Rd, MS H24-6, Atlanta, GA 30329 (fhavers@cdc.gov).

Published Online: July 21, 2020. doi:10.1001/jamainternmed.2020.4130

Author Contributions: Drs Havers and Lim had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.

Study concept and design: Havers, Reed, Lim, Hall, Fry, Owen, Blackmore, Blog, Lindquist, Turabelidze, Wiesman, Schiffer, Thornburg.

Acquisition, analysis, or interpretation of data: Havers, Reed, Lim, Montgomery, Klena, Cannon, Chiang, Gibbons, Krapiunaya, Morales-Betoulle, Roguski, Rasheed, Freeman, Lester, Mills, Carroll, Owen, Johnson, Semenova, Blog, Chai, Dunn, Hand, Jain, Lynfield, Pritchard, Sokol, Sosa, Watkins, Williams, Yendell, Schiffer, Thornburg.

Drafting of the manuscript: Havers, Lim, Klena, Fry, Thornburg.

Critical revision of the manuscript for important intellectual content: All authors.

Statistical analysis: Havers, Lim, Gibbons, Roguski, Schiffer.

Obtained funding: Havers.

Administrative, technical, or material support: Havers, Montgomery, Klena, Cannon, Chiang, Morales-Betoulle, Mills, Carroll, Owen, Johnson, Semenova, Blackmore, Blog, Chai, Dunn, Jain, Lindquist, Pritchard, Sokol, Sosa, Turabelidze, Watkins, Wiesman, Williams, Schiffer, Thornburg.

Study supervision: Havers, Reed, Montgomery, Hall, Fry, Johnson, Blog, Pritchard, Schiffer, Thornburg.

Conflict of Interest Disclosures: Dr Wiesman reported receiving grants from US Department of Health and Human Services during the conduct of the study. No other disclosures were reported.

Funding/Support: This work was supported by the Centers for Disease Control and Prevention, Atlanta, Georgia.

Role of the Funder/Sponsor: The Centers for Disease Control and Prevention was involved in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, and approval of the manuscript; and decision to submit the manuscript for publication.

Group Information: The author members of the CDC COVID-19 Response Team are Drs Havers, Reed, Lim, Montgomery, Klena, Hall, Fry, Chiang, Morales-Betoulle, Rasheed, Freeman, Lester, Mills, Carroll, Owen, Johnson, Semenova, and Thornburg; Mses Cannon, Gibbons, Krapiunaya, and Roguski; and Mr Schiffer. The author members of the State Collaborator Group are Drs Blackmore, Blog, Chai, Dunn, Jain, Lindquist, Lynfield, Sosa, Turabelidze, Watkins, Wiesman, Williams, and Yendell; Mses Hand and Sokol; and Mr Pritchard.

Disclaimer: The findings and conclusions in the article are those of the authors and do not necessarily represent the views of the US Centers for Disease Control and Prevention.

Additional Contributions: We thank LabCorp and Quest for supplying specimens. From Quest: William A. Meyer III, PhD, Larry A. Hirsch, BS, Taylor Hwang, BS, and Janet M. Rochat, MS. From the New York City Department of Mental Health and Hygiene: Marcelle Layton, MD. From the Centers for Disease Control and Prevention Molecular Pathogenesis and Immunology Research Laboratory team: Bailey Alston, MS, Muyiwa Ategbole, MPH, Shanna Bolcen, MSPH, Darbi Boulay, BS, Peter Browning, BS, Li Cronin, MS, Ebenezer David, PhD, Rita Desai, BS, Monica Epperson, PhD, Yamini Gorantla, PhD, Lily Jia, MS, Han Li, PhD, Pete Maniatis, MS, Jeff Martin, BA, Kimberly Moss, BS, Kristina Ortiz, MS, Palak Patel, MS, So Hee Park, BS, Yunlong Qin, PhD, Evelene Steward-Clark, MS, Heather Tatum, BS, Andrew Vogan, MS, and Briana Zellner, PhD. We also thank Ian E. Fellows, PhD, of Fellows Statistics for input on statistical methodology. These individuals were not compensated directly by CDC for their participation in this specific study.