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Coronavirus (COVID-19)

Clarifying the Sweeping Consequences of COVID-19 in Pregnant Women, Newborns, and Children With Existing Cohorts

Educational Objective
To understand the consequences of COVID-19 in Pregnant Women, Newborns, and Children with existing cohorts

1 Credit CME

JAMA Pediatrics

Published Online: August 10, 2020

Viewpoint

Article Information and Disclosures

Yanhong Jessika Hu, PhD^1,2;

Melissa Wake, MD^1,2;

Richard Saffery, PhD^1,2

Author Affiliations

¹Murdoch Children’s Research Institute, Royal Children’s Hospital, Parkville, Victoria, Australia
²Department of Paediatrics, The University of Melbourne, Parkville, Victoria, Australia

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The sweeping consequences of the coronavirus disease 2019 (COVID-19) pandemic for pregnant women, newborns, and children remain uncharted. The greatest outcomes may not be on those with known infections, who have dominated the early avalanche of literature. Interactions between humans and viruses evolve over time, judging from previous pandemic histories, and we will soon lose the opportunity to understand the current one. This Viewpoint suggests that the only way to truly capture the long-term consequences of the COVID-19 pandemic for these groups may be in agile reconfiguration of existing, large birth cohort studies.

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Article Information

Corresponding Author: Melissa Wake, MD, Murdoch Children’s Research Institute, The Royal Children’s Hospital, Flemington Road, Parkville, VIC 3052, Australia (melissa.wake@mcri.edu.au).

Published Online: August 10, 2020. doi:10.1001/jamapediatrics.2020.2395

Conflict of Interest Disclosures: Dr Wake is supported by Australian National Health & Medical Research Council Principal Research Fellowship (grant 1160906). No other disclosures were reported.

Additional Contributions: We thank Joseph Irvin Harwell, MD, Brown University, for his comments. He was not compensated for his contributions.

References

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Khan MMA , Khan MN , Mustagir MG , Rana J , Haque MR , Rahman MM . COVID-19 infection during pregnancy: a systematic review to summarize possible symptoms, treatments, and pregnancy outcomes. Published April 10, 2020. Accessed June 26, 2020. https://www.medrxiv.org/content/10.1101/2020.03.31.20049304v2

de Souza TH , Nadal JA , Nogueira RJN , Pereira RM , Brandao MB . Clinical manifestations of children with COVID-19: a systematic review. Published April 14, 2020. Accessed June 26, 2020. https://www.medrxiv.org/content/10.1101/2020.04.01.20049833v2

Hong H , Wang Y , Chung H-T , Chen C-J . Clinical characteristics of novel coronavirus disease 2019 (COVID-19) in newborns, infants and children. Pediatr Neonatol. 2020;61(2):131-132. doi:10.1016/j.pedneo.2020.03.001 PubMed Google Scholar Crossref

Sutton D , Fuchs K , D’Alton M , Goffman D . Universal screening for SARS-CoV-2 in women admitted for delivery. N Engl J Med. 2020;382(22):2163-2164. doi:10.1056/NEJMc2009316 PubMed Google Scholar Crossref

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UK Biobank. UK Biobank makes health data available to tackle COVID-19. Published April 14, 2020. Accessed June 26, 2020. https://www.ukbiobank.ac.uk/2020/04/covid/

Johns Hopkins School & Medicine. COVID-19 dashboard by the Center for Systems Science and Engineering (CSSE) at Johns Hopkins University. Published 2020. Accessed June 26, 2020. https://coronavirus.jhu.edu/map.html

AMA CME Accreditation Information

Credit Designation Statement: The American Medical Association designates this Journal-based CME activity activity for a maximum of 1.00  AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to:

1.00 Medical Knowledge MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program;;
1.00 Self-Assessment points in the American Board of Otolaryngology – Head and Neck Surgery’s (ABOHNS) Continuing Certification program;
1.00 MOC points in the American Board of Pediatrics’ (ABP) Maintenance of Certification (MOC) program;
1.00 Lifelong Learning points in the American Board of Pathology’s (ABPath) Continuing Certification program; and
1.00 CME points in the American Board of Surgery’s (ABS) Continuing Certification program

It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting MOC credit.