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With more than 20 million cases of coronavirus disease 2019 (COVID-19) globally and now exceeding 5 million cases in the United States, the COVID-19 pandemic represents one of the greatest public health challenges in more than a century. To succeed against COVID-19, multiple public health tools and interventions will be needed to minimize morbidity and mortality related to COVID-19. Although extreme public health interventions, for example, lockdowns and stay-at-home mandates, were initially critical to flattening the curve, many fundamental questions remain, such as when can employees deemed nonessential return to work, how can children safely return to school, and who should be first to receive a vaccine once it becomes available. Information about who is at highest risk of hospitalization, intensive care unit admission, and death based on age, sex, race/ethnicity, and underlying conditions is now becoming available.1 In addition, the relationship between neighborhood factors (eg, increased neighborhood household crowding rate) and risks for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and COVID-19 disease outcomes are now recognized.2
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Corresponding Author: Sonja A. Rasmussen, MD, MS, University of Florida, 1600 SW Archer Rd, PO Box 100296, Gainesville, FL 32610 (firstname.lastname@example.org).
Published Online: August 12, 2020. doi:10.1001/jama.2020.14992
Conflict of Interest Disclosures: Dr del Rio reported receiving grants from the Emory Vaccine and Treatment Evaluation Unit outside the submitted work. No other disclosures were reported.
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