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The global struggle against coronavirus disease 2019 (COVID-19) is now in its eighth month since the pandemic virus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first emerged. The severe economic, personal, and psychological adverse effects of shutdowns and social distancing make these effective preventive measures challenging to sustain long-term. In 1999, just before the launch of a new millennium, the Centers for Disease Control and Prevention listed vaccines as the most important public health achievement of the 20th century.1 According to one estimate, more than 42 000 children’s lives are saved annually as a result of the US programs of routine childhood immunizations.2 Safe and effective COVID-19 vaccines could lead to a level of global immunity that stops the pandemic. This is the anti–COVID-19 intervention most public health leaders and many people long for the most.
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Corresponding Author: Mark J. Mulligan, MD, NYU Grossman School of Medicine, Alexandria Center for Life Sciences (West Tower), 430 E 29th St, Room 304, New York, NY 10016 (email@example.com).
Published Online: August 13, 2020. doi:10.1001/jama.2020.15539
Conflict of Interest Disclosures: Dr Mulligan reported receiving grants from the National Institutes of Health/National Institute of Allergy and Infectious Diseases, Eli Lilly, Pfizer, and Sanofi and personal fees from Meissa Vaccines.
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