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Characteristics and Outcomes of COVID-19 Patients During Initial Peak and Resurgence in the Houston Metropolitan Area

Educational Objective
To understand the characteristics and outcomes of COVID-19 parents during the initial peak and resurgence in Houston
1 Credit CME

Texas is experiencing resurgence of coronavirus disease 2019 (COVID-19). We report sociodemographic, clinical, and outcome differences across the first and second surges of COVID-19 hospitalizations at Houston Methodist, an 8-hospital health care system in Houston, Texas.1

From electronic health records, we identified patients with positive reverse transcriptase–polymerase chain reaction (RT-PCR) nasopharyngeal swab test results for severe acute respiratory syndrome coronavirus 2. We extracted age, sex, race/ethnicity, comorbidity, medication, intensive care unit (ICU) admission, and mortality information. The assessment of race/ethnicity was driven by prior analyses of our data that demonstrated higher SARS-CoV-2 infection rates among racial and ethnic minorities.2 We tracked daily total, ICU, and non-ICU (medical/surgical units) hospital census across the reporting period. We categorized patients into surge 1 for admissions between March 13 and May 15, 2020, and surge 2 between May 16 and July 7, 2020. Surge 2 started 2 weeks after a phased statewide reopening.3

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CME Disclosure Statement: Unless noted, all individuals in control of content reported no relevant financial relationships. If applicable, all relevant financial relationships have been mitigated.

Article Information

Corresponding Author: Robert A. Phillips, MD, PhD, Houston Methodist, 6565 Fannin St, Dunn 200, Houston, TX 77030 (raphillips@houstonmethodist.org).

Accepted for Publication: July 28, 2020.

Published Online: August 13, 2020. doi:10.1001/jama.2020.15301

Author Contributions: Dr Vahidy and Mr Askary had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.

Concept and design: Vahidy, Drews, Masud, Boom, Phillips.

Acquisition, analysis, or interpretation of data: All authors.

Drafting of the manuscript: Vahidy, Schwartz, Phillips.

Critical revision of the manuscript for important intellectual content: Vahidy, Drews, Masud, Askary, Boom, Phillips.

Statistical analysis: Vahidy.

Administrative, technical, or material support: Drews, Masud, Schwartz, Boom, Phillips.

Supervision: Drews, Boom, Phillips.

Conflict of Interest Disclosures: Dr Masud reports being a consultant for Portolla. No other disclosures were reported.

Additional Contributions: We thank Sayali Kelkar, MPH, Houston Methodist, for help with data curation and assimilation for this analysis. Ms Kelkar did not receive financial compensation for her contribution.

References
1.
Tittle  S , Braxton  C , Schwartz  RL ,  et al  A guide for surgical and procedural recovery after the first surge of Covid-19.   NEJM Catalyst. Published July 2, 2020. Accessed August 4, 2020. https://catalyst.nejm.org/doi/full/10.1056/cat.20.0287Google Scholar
2.
Vahidy  FS , Nicolas  JC , Meeks  JR ,  et al.  Racial and ethnic disparities in SARS-CoV-2 pandemic: analysis of a COVID-19 observational registry for a diverse US metropolitan population.   medRxiv. Preprint posted online May 12, 2020. doi:10.1101/2020.04.24.20073148Google Scholar
3.
Office of the Texas Governor.  Governor’s strike force to open Texas.  Published 2020. Accessed July 14, 2020. https://open.texas.gov/
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