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Critical Care Medicine

Characteristics and Outcomes of COVID-19 Patients During Initial Peak and Resurgence in the Houston Metropolitan Area

Educational Objective
To understand the characteristics and outcomes of COVID-19 parents during the initial peak and resurgence in Houston

1 Credit CME

JAMA

Published Online: August 13, 2020

Research Letter

Article Information and Disclosures

Farhaan S. Vahidy, PhD, MBBS, MPH¹;

Ashley L. Drews, MD²;

Faisal N. Masud, MD³;

Roberta L. Schwartz, PhD⁴;

Belimat “Billy” Askary, MA⁵;

Marc L. Boom, MD²;

Robert A. Phillips, MD, PhD¹

Author Affiliations

¹Center for Outcomes Research, Houston Methodist Research Institute, Houston, Texas
²Department of Medicine, Houston Methodist, Houston, Texas
³Department of Anesthesiology and Critical Care, Houston Methodist, Houston, Texas
⁴Houston Methodist Academic Institute, Houston Methodist, Houston, Texas
⁵System Quality and Patient Safety, Houston Methodist, Houston, Texas

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Characteristics and Outcomes of Critically Ill Patients With COVID-19 in Washington State

Matt Arentz, MD; Eric Yim, MD; Lindy Klaff, MD; Sharukh Lokhandwala, MD, MSc; Francis X. Riedo, MD; Maria Chong, MD; Melissa Lee, MD
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Clinical Characteristics, Comorbidities, and Outcomes Among Patients With COVID-19 Hospitalized in the NYC Area

Safiya Richardson, MD, MPH; Jamie S. Hirsch, MD, MA, MSB; Mangala Narasimhan, DO; James M. Crawford, MD, PhD; Thomas McGinn, MD, MPH; Karina W. Davidson, PhD, MASc; and the Northwell COVID-19 Research Consortium; Douglas P. Barnaby, MD, MSc; Lance B. Becker, MD; John D. Chelico, MD, MA; Stuart L. Cohen, MD; Jennifer Cookingham, MHA; Kevin Coppa, BS; Michael A. Diefenbach, PhD; Andrew J. Dominello, BA; Joan Duer-Hefele, RN, MA; Louise Falzon, BA, PGDipInf; Jordan Gitlin, MD; Negin Hajizadeh, MD, MPH; Tiffany G. Harvin, MBA; David A. Hirschwerk, MD; Eun Ji Kim, MD, MS, MS; Zachary M. Kozel, MD; Lyndonna M. Marrast, MD, MPH; Jazmin N. Mogavero, MA; Gabrielle A. Osorio, MPH; Michael Qiu, MD, PhD; Theodoros P. Zanos, PhD
Original Investigation

Clinical Characteristics of Patients With COVID-19 Receiving Emergency Medical Services

Betty Y. Yang, MD; Leslie M. Barnard, MPH; Jamie M. Emert, MPH; Christopher Drucker, PhD; Leilani Schwarcz, MPH; Catherine R. Counts, PhD; David L. Murphy, MD; Sally Guan, BA; Kosuke Kume, BS; Karen Rodriquez, BA; Tracie Jacinto, BA; Susanne May, PhD; Michael R. Sayre, MD; Thomas Rea, MD, MPH
Research Letter

Prevalence of SARS-CoV-2 Infection Among Health Care Workers in Houston, Texas

Farhaan S. Vahidy, PhD, MBBS, MPH; David W. Bernard, MD, PhD; Marc L. Boom, MD, MBA; Ashley L. Drews, MD; Paul Christensen, MD; Jeremy Finkelstein, MD; Roberta L. Schwartz, PhD
Research Letter

Community-Level Disparities in COVID-19 Infections and Deaths in Large US Metropolitan Areas

Samrachana Adhikari, PhD; Nicholas P. Pantaleo, MPH; Justin M. Feldman, ScD; Olugbenga Ogedegbe, MD; Lorna Thorpe, PhD; Andrea B. Troxel, ScD

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Texas is experiencing resurgence of coronavirus disease 2019 (COVID-19). We report sociodemographic, clinical, and outcome differences across the first and second surges of COVID-19 hospitalizations at Houston Methodist, an 8-hospital health care system in Houston, Texas.¹

From electronic health records, we identified patients with positive reverse transcriptase–polymerase chain reaction (RT-PCR) nasopharyngeal swab test results for severe acute respiratory syndrome coronavirus 2. We extracted age, sex, race/ethnicity, comorbidity, medication, intensive care unit (ICU) admission, and mortality information. The assessment of race/ethnicity was driven by prior analyses of our data that demonstrated higher SARS-CoV-2 infection rates among racial and ethnic minorities.² We tracked daily total, ICU, and non-ICU (medical/surgical units) hospital census across the reporting period. We categorized patients into surge 1 for admissions between March 13 and May 15, 2020, and surge 2 between May 16 and July 7, 2020. Surge 2 started 2 weeks after a phased statewide reopening.³

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Article Information

Corresponding Author: Robert A. Phillips, MD, PhD, Houston Methodist, 6565 Fannin St, Dunn 200, Houston, TX 77030 (raphillips@houstonmethodist.org).

Accepted for Publication: July 28, 2020.

Published Online: August 13, 2020. doi:10.1001/jama.2020.15301

Author Contributions: Dr Vahidy and Mr Askary had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.

Concept and design: Vahidy, Drews, Masud, Boom, Phillips.

Acquisition, analysis, or interpretation of data: All authors.

Drafting of the manuscript: Vahidy, Schwartz, Phillips.

Critical revision of the manuscript for important intellectual content: Vahidy, Drews, Masud, Askary, Boom, Phillips.

Statistical analysis: Vahidy.

Administrative, technical, or material support: Drews, Masud, Schwartz, Boom, Phillips.

Supervision: Drews, Boom, Phillips.

Conflict of Interest Disclosures: Dr Masud reports being a consultant for Portolla. No other disclosures were reported.

Additional Contributions: We thank Sayali Kelkar, MPH, Houston Methodist, for help with data curation and assimilation for this analysis. Ms Kelkar did not receive financial compensation for her contribution.

References

Tittle S , Braxton C , Schwartz RL , et al A guide for surgical and procedural recovery after the first surge of Covid-19. NEJM Catalyst. Published July 2, 2020. Accessed August 4, 2020. https://catalyst.nejm.org/doi/full/10.1056/cat.20.0287 Google Scholar

Vahidy FS , Nicolas JC , Meeks JR , et al. Racial and ethnic disparities in SARS-CoV-2 pandemic: analysis of a COVID-19 observational registry for a diverse US metropolitan population. medRxiv. Preprint posted online May 12, 2020. doi:10.1101/2020.04.24.20073148 Google Scholar

Office of the Texas Governor. Governor’s strike force to open Texas. Published 2020. Accessed July 14, 2020. https://open.texas.gov/

AMA CME Accreditation Information

Credit Designation Statement: The American Medical Association designates this Journal-based CME activity activity for a maximum of 1.00  AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to:

1.00 Medical Knowledge MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program;;
1.00 Self-Assessment points in the American Board of Otolaryngology – Head and Neck Surgery’s (ABOHNS) Continuing Certification program;
1.00 MOC points in the American Board of Pediatrics’ (ABP) Maintenance of Certification (MOC) program;
1.00 Lifelong Learning points in the American Board of Pathology’s (ABPath) Continuing Certification program; and
1.00 CME points in the American Board of Surgery’s (ABS) Continuing Certification program

It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting MOC credit.