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Coronavirus (COVID-19)

Nephrology and COVID-19

Educational Objective
To understand how COVID-19 is impacting the field of nephrology

1 Credit CME

JAMA

Published Online: September 22/29, 2020

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Article Information and Disclosures

Wolfgang C. Winkelmayer, MD, MPH, ScD^1,2;

Pascale Khairallah, MD¹;

David M. Charytan, MD³

Author Affiliations

¹Section of Nephrology, Baylor College of Medicine, Houston, Texas
²Associate Editor, JAMA
³Division of Nephrology, New York University Grossman School of Medicine, New York, New York

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Dost Öngür, MD, PhD; Roy Perlis, MD, MSc; Donald Goff, MD
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Dimitri A. Christakis, MD, MPH
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Robert O. Bonow, MD, MS; Patrick T. O’Gara, MD; Clyde W. Yancy, MD, MSc
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Rita F. Redberg, MD, MSc; Mitchell Katz, MD; Robert Steinbrook, MD
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Frederick P. Rivara, MD, MPH; Stephan D. Fihn, MD, MPH; Eli N. Perencevich, MD, MS
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Kanade Shinkai, MD, PhD; Anna L. Bruckner, MD, MSCS
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Mary L. Disis, MD
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Neil M. Bressler, MD
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John Z. Ayanian, MD, MPP

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Initial reports about the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic suggested that the incidence of kidney complications was low.¹^,2 Few would have anticipated the profound effect that the coronavirus disease 2019 (COVID-19) pandemic would have on the field of kidney health care. Early in the pandemic, it became apparent that patients with kidney disease were particularly vulnerable to SARS-CoV-2.³ In addition, it also became apparent that acute kidney injury (AKI) was occurring at several-fold higher rates in hospitalized patients with COVID-19 in the US than in earlier series in China.

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Article Information

Corresponding Author: Wolfgang C. Winkelmayer, MD, MPH, ScD, Section of Nephrology, Baylor College of Medicine, One Baylor Plaza, Ste ABBR R705, MS 395, Houston, TX 77030 (winkelma@bcm.edu).

Conflict of Interest Disclosures: Dr Winkelmayer reported receipt of personal fees from Akebia, AstraZeneca, Bayer, Daichii-Sankyo, Janssen, Merck, Relypsa, and Vifor Fresenius Medical Care Renal Pharma and grants from the National Institutes of Health. Dr Charytan reported receipt of personal fees from PLC Medical, Janssen, GlaxoSmithKline, Merck, and Fresenius; grants and personal fees from Gilead, AstraZeneca, and Amgen; and grants from Bioporto. No other disclosures were reported.

References

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Guan WJ , Ni ZY , Hu Y , et al. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med. 2020;382(18):1708-1720. doi:10.1056/NEJMoa2002032 PubMed Google Scholar Crossref

Kliger AS , Silberzweig J . Mitigating risk of COVID-19 in dialysis facilities. Clin J Am Soc Nephrol. 2020;15(5):707-709. doi:10.2215/CJN.03340320 PubMed Google Scholar Crossref

Rezoagli E , McNicholas B , Pham T , et al. Lung-kidney cross-talk in the critically ill. Intensive Care Med. 2020;46(5):1072-1073. doi:10.1007/s00134-020-05962-2 PubMed Google Scholar Crossref

Su H , Yang M , Wan C , et al. Renal histopathological analysis of 26 postmortem findings of patients with COVID-19 in China. Kidney Int. 2020;98(1):219-227. doi:10.1016/j.kint.2020.04.003 PubMed Google Scholar Crossref

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Goldfarb DS , Benstein JA , Zhdanova O , et al. Impending shortages of kidney replacement therapy for COVID-19 patients. Clin J Am Soc Nephrol. 2020;15(6):880-882. doi:10.2215/CJN.05180420 PubMed Google Scholar Crossref

Chan L , Chaudhary K , Saha A , et al. Acute kidney injury in hospitalized patients with COVID-19. medRxiv. Preprint posted May 8, 2020. doi:10.1101/2020.05.04.20090944

Loupy A , Aubert O , Reese PP , et al. Organ procurement and transplantation during the COVID-19 pandemic. Lancet. 2020;395(10237):e95-e96. doi:10.1016/S0140-6736(20)31040-0 PubMed Google Scholar Crossref

Boyarsky BJ , Werbel WA , Durand CM , et al. Early national and center-level changes to kidney transplantation in the United States during the COVID-19 epidemic. Am J Transplant. Published online June 28, 2020. doi:10.1111/ajt.16167 PubMed Google Scholar

AMA CME Accreditation Information

Credit Designation Statement: The American Medical Association designates this Journal-based CME activity activity for a maximum of 1.00  AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to:

1.00 Medical Knowledge MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program;;
1.00 Self-Assessment points in the American Board of Otolaryngology – Head and Neck Surgery’s (ABOHNS) Continuing Certification program;
1.00 MOC points in the American Board of Pediatrics’ (ABP) Maintenance of Certification (MOC) program;
1.00 Lifelong Learning points in the American Board of Pathology’s (ABPath) Continuing Certification program; and
1.00 CME points in the American Board of Surgery’s (ABS) Continuing Certification program

It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting MOC credit.