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Cerebrospinal Fluid Leak After Nasal Swab Testing for Coronavirus Disease 2019

Educational Objective
To understand how a cerebrospinal fluid leak after nasal swabbing can affect testing for COVID-19
1 Credit CME

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CME Disclosure Statement: Unless noted, all individuals in control of content reported no relevant financial relationships. If applicable, all relevant financial relationships have been mitigated.

Article Information

Corresponding Author: Jarrett Walsh, MD, PhD, Department of Otolaryngology–Head and Neck Surgery, University of Iowa Hospitals and Clinics, 200 Hawkins Dr, 21264 PFP, Iowa City, IA 52242 (jarrett-walsh@uiowa.edu).

Published Online: October 1, 2020. doi:10.1001/jamaoto.2020.3579

Correction: This article was corrected on November 5, 2020, to fix an ommission in co-first authorship in the end matter.

Conflict of Interest Disclosures: Dr Walsh reported a patent to apparatus, systems and methods for negative pressure face shielding pending and a patent to apparatus, systems and methods for unified endoscopic procedure performance and visualization pending. No other disclosures were reported.

Additional Contributions: We thank the patient for granting permission to publish this information.

Additional Information: Drs Sullivan and Schwalje were co-first authors.

References
1.
World Health Organization. COVID-19 Strategic Preparedness and Response Plan, 2020. https://www.who.int/docs/default-source/coronaviruse/covid-19-sprp-unct-guidelines.pdf. Accessed July 29, 2020.
2.
Interim Guidelines for Collecting, Handling, and Testing Clinical Specimens for COVID-19. Published 2020. https://www.cdc.gov/coronavirus/2019-ncov/lab/guidelines-clinical-specimens.html. Accessed July 29, 2020.
3.
Daele  JJM , Goffart  Y , Machiels  S .  Traumatic, iatrogenic, and spontaneous cerebrospinal fluid (CSF) leak: endoscopic repair.   B-ENT. 2011;7(suppl 17):47-60. https://www.ncbi.nlm.nih.gov/pubmed/22338375.PubMedGoogle Scholar
4.
Bialer  OY , Rueda  MP , Bruce  BB , Newman  NJ , Biousse  V , Saindane  AM .  Meningoceles in idiopathic intracranial hypertension.   AJR Am J Roentgenol. 2014;202(3):608-613. doi:10.2214/AJR.13.10874PubMedGoogle ScholarCrossref
5.
Tromberg  BJ , Schwetz  TA , Pérez-Stable  EJ ,  et al.  Rapid scaling up of Covid-19 diagnostic testing in the United States—the NIH RADx initiative.   N Engl J Med. 2020;383(11):1071-1077. doi:10.1056/NEJMsr2022263PubMedGoogle ScholarCrossref
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