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Building Trust to Achieve Confidence in COVID-19 Vaccines

Educational Objective
To identify the key insights or developments described in this article
1 Credit CME

Kreps and colleagues’ survey1 of a national sample of US adults provides insights into how we might achieve the level of vaccine uptake needed to prevent the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This study lands at a critical moment for US public health. The SARS-CoV-2 pandemic is surging, influenza season is looming, and the delivery of a vaccine to protect against coronavirus disease 2019 (COVID-19), the disease caused by SARS-CoV-2, appears imminent through the US government’s Operation Warp Speed initiative.

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Article Information

Published: October 20, 2020. doi:10.1001/jamanetworkopen.2020.25672

Open Access: This is an open access article distributed under the terms of the CC-BY License. © 2020 Opel DJ et al. JAMA Network Open.

Corresponding Author: Douglas J. Opel MD, MPH, Seattle Children’s Research Institute, 1900 Ninth Ave, M/S: JMB-6, Seattle, WA 98101 (djopel@uw.edu).

Conflict of Interest Disclosures: Dr Salmon reported receiving personal fees from Merck and grants from Walgreens outside the submitted work. No other disclosures were reported.

References
1.
Kreps  S , Prasad  S , Brownstein  JS ,  et al.  Factors associated with US adults’ likelihood of accepting COVID-19 vaccination.   JAMA Netw Open. 2020;3(10):e2025594. doi:10.1001/jamanetworkopen.2020.25594Google Scholar
2.
Bish  A , Yardley  L , Nicoll  A , Michie  S .  Factors associated with uptake of vaccination against pandemic influenza: a systematic review.   Vaccine. 2011;29(38):6472-6484. doi:10.1016/j.vaccine.2011.06.107PubMedGoogle ScholarCrossref
3.
Determann  D , Korfage  IJ , Lambooij  MS ,  et al.  Acceptance of vaccinations in pandemic outbreaks: a discrete choice experiment.   PLoS One. 2014;9(7):e102505. doi:10.1371/journal.pone.0102505PubMedGoogle Scholar
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Shah  A , Marks  PW , Hahn  SM .  Unwavering regulatory safeguards for COVID-19 vaccines.   JAMA. 2020. doi:10.1001/jama.2020.15725PubMedGoogle Scholar
5.
Quinn  SC , Kumar  S , Freimuth  VS , Kidwell  K , Musa  D .  Public willingness to take a vaccine or drug under Emergency Use Authorization during the 2009 H1N1 pandemic.   Biosecur Bioterror. 2009;7(3):275-290. doi:10.1089/bsp.2009.0041PubMedGoogle ScholarCrossref
6.
Liu  BF , Quinn  SC , Egnoto  M , Freimuth  V , Boonchaisri  N .  Public understanding of medical countermeasures.   Health Secur. 2017;15(2):194-206. doi:10.1089/hs.2016.0074PubMedGoogle ScholarCrossref
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US Food and Drug Administration. Authorization of emergency use of anthrax vaccine adsorbed for prevention of inhalation anthrax by individuals at heightened risk of exposure due to attack with anthrax. Federal Register, Published February 2, 2005. Accessed September 6, 2020. https://www.federalregister.gov/documents/2005/02/02/05-2028/authorization-of-emergency-use-of-anthrax-vaccine-adsorbed-for-prevention-of-inhalation-anthrax-by
8.
The Harris Poll. Poll: most Americans believe the Covid-19 vaccine approval process is driven by politics, not science. Accessed September 7, 2020. https://theharrispoll.com/poll-most-americans-believe-the-covid-19-vaccine-approval-process-is-driven-by-politics-not-science/
9.
World Health Organization. Ten threats to global health in 2019. Published March 21, 2019. Accessed October 9, 2019. https://www.who.int/vietnam/news/feature-stories/detail/ten-threats-to-global-health-in-2019
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