Accepted for Publication: October 1, 2020.
Published Online: October 20, 2020. doi:10.1001/jamainternmed.2020.6820
Corresponding author: Olivier Hermine, MD, PhD, Université de Paris, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Necker, INSERM, Imagine Institute, 149-161 rue de Sèvres, Paris 75743, France (ohermine@gmail.com).
Correction: This article was corrected on January 4, 2021, to fix errors in the supplemental group member list and to add the collaborative group in the end matter. These collaborators were previously not indexed in PubMed, but the error has been resolved. It was corrected again on May 3, 2021, to correct the spelling of 2 names in the nonauthor collaborators list in the Supplement.
Author Contributions: Drs Resche-Rigon and Porcher had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis. The authors contributed equally to this study.
Concept and design: All authors.
Acquisition, analysis, or interpretation of data: All authors.
Drafting of the manuscript: All authors.
Critical revision of the manuscript for important intellectual content: Hermine, Mariette, Tharaux, Resche-Rigon.
Statistical analysis: Porcher, Ravaud.
Obtained funding: Hermine, Mariette, Resche-Rigon, Ravaud.
Administrative, technical, or material support: Hermine, Mariette, Resche-Rigon, Ravaud.
Supervision: Hermine, Mariette, Tharaux, Ravaud.
Conflict of Interest Disclosures: Dr Tharaux has received honorarium fees for participation on advisory boards for Retrophin Inc not related to this work. No other disclosures are reported.
Data Sharing Statement: See Supplement 3.
Funding/Support: This trial was publicly funded (Ministry of Health, Programme Hospitalier de Recherche Clinique [PHRC COVID-19-20-0143, PHRC COVID-19-20-0029], Foundation for Medical Research (FRM), AP-HP Foundation and the Reacting program).
The CORIMUNO-19 Collaborative Group: The CORIMUNO-19 Collaborative Group members are listed in Supplement 4.
Role of the Funder/Sponsor: The funding agencies had no access to the trial data and had no role in the design, conduct or reporting of the trial. Roche donated TCZ in unrestricted grant, and had no role in the trial design or conduct; the collection, management, analysis, interpretation of the data; or in the preparation, review of the manuscript or the approval of the manuscript for submission.
Additional Contributions: We are grateful to all patients who participated in the CORIMUNO study, and their families. The authors also thank Pr Maxime Dougados, MD, in charge of the logistics, as well as the investigators who collaborated in this study (Supplement 4) and Universities of Paris, Paris-Saclay, Paris-Sorbonne, Paris-Nord Sorbonne, Paris-Est Créteil, Versailles-Saint Quentin, Strasbourg and Lille (Medical Students support), INSERM, and Reacting.
Additional Information: A coordination committee was responsible for the design, conduct, and reporting of the trial, and an independent data and safety monitoring board (DSMB) oversees all CORIMUNO trials (Supplement 4).