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Shifting Hydroxychloroquine Patterns Raise Concern

Educational Objective
To identify the key insights or developments described in this article
1 Credit CME

The number of hydroxychloroquine prescriptions by specialists who don’t typically prescribe the drug skyrocketed after preliminary reports in March suggested potential benefits for patients with coronavirus disease 2019 (COVID-19).

CDC investigators analyzed hydroxychloroquine and chloroquine prescriptions dispensed by US retail pharmacies from January through June 2019 and during the same period in 2020. Prior to 2020, the drugs were prescribed most often by primary care physicians or specialists like rheumatologists or dermatologists for autoimmune disorders or as malaria prophylaxis.

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The number of hydroxychloroquine prescriptions by specialists who don’t typically prescribe the drug skyrocketed after preliminary reports in March suggested potential benefits for patients with coronavirus disease 2019 (COVID-19).

CDC investigators analyzed hydroxychloroquine and chloroquine prescriptions dispensed by US retail pharmacies from January through June 2019 and during the same period in 2020. Prior to 2020, the drugs were prescribed most often by primary care physicians or specialists like rheumatologists or dermatologists for autoimmune disorders or as malaria prophylaxis.

However, the analysis showed that prescriptions written by specialists who don’t typically use the drugs rose to 75 569 in March 2020 from 1143 in February 2020—an 80-fold increase compared with March 2019. Among specialists who don’t routinely prescribe hydroxychloroquine and chloroquine, the greatest growth in outpatient prescriptions in March 2020 was in the fields of ophthalmology, anesthesiology, and cardiology.

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