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Scientific and Ethical Principles Underlying Recommendations From the Advisory Committee on Immunization Practices for COVID-19 Vaccination Implementation

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To identify the key insights or developments described in this article
1 Credit CME
JAMA
November 24, 2020
Viewpoint
Beth P. Bell, MD, MPH1;
José R. Romero, MD2,3;
Grace M. Lee, MD, MPH4
Author Affiliations
  • 1Department of Global Health, University of Washington, Seattle
  • 2University of Arkansas for Medical Sciences, Little Rock
  • 3Arkansas Department of Health, Little Rock
  • 4Stanford University School of Medicine, Stanford Children’s Health, Stanford, California
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The continued global spread of the coronavirus disease 2019 (COVID-19) pandemic highlights the pressing need for safe and effective COVID-19 vaccines. Vaccine development efforts of unprecedented scale and speed are being pursued. Since June 2020, the Advisory Committee on Immunization Practices (ACIP) has held 4 public meetings to lay the groundwork for public health recommendations for COVID-19 vaccines. This Viewpoint summarizes the approach ACIP is taking in formulating recommendations, with a focus on the ethical principles and potential groups for allocation of vaccine doses when supply is limited. Recommendations will be issued after reviewing safety and effectiveness data and vaccines are licensed or authorized under Emergency Use Authorization by the Food and Drug Administration (FDA).

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CME Disclosure Statement: Unless noted, all individuals in control of content reported no relevant financial relationships. If applicable, all relevant financial relationships have been mitigated.

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Vaccination Ethics Public Health Coronavirus (COVID-19)
Article Information

Corresponding Author: Beth P. Bell, MD, MPH, Department of Global Health, University of Washington, Box 357965, Seattle, WA 98195 (bzb8@uw.edu).

Published Online: October 22, 2020. doi:10.1001/jama.2020.20847

Conflict of Interest Disclosures: None reported.

Additional Information: In addition to the authors, voting members of ACIP include Robert L. Atmar, MD, Kevin A. Ault, MD, Lynn Bahta, RN, MPH, Henry Bernstein, DO, Sharon E. Frey, MD, Paul Hunter, MD, Veronica V. McNally, JD, Katherine A. Poehling, MD, Pablo J. Sánchez, MD, Peter G. Szilagyi, MD, and Helen Keipp Talbot, MD. This Viewpoint reflects the opinion of the entire committee.

References
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Lee  GM , Bell  BP , Romero  JR .  The Advisory Committee on Immunization Practices and its role in the pandemic vaccine response.   JAMA. 2020;324(6):546-547. doi:10.1001/jama.2020.13167PubMedGoogle ScholarCrossref
2.
World Health Organization. WHO SAGE values framework for the allocation and prioritization of COVID-19 vaccination. https://apps.who.int/iris/bitstream/handle/10665/334299/WHO-2019-nCoV-SAGE_Framework-Allocation_and_prioritization-2020.1-eng.pdf
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National Academies of Sciences, Engineering, and Medicine.  Framework for Equitable Allocation of COVID-19 Vaccine. National Academies Press; 2020.
4.
Persad  G , Peek  ME , Emanuel  EJ .  Fairly prioritizing groups for access to COVID-19 vaccines.   JAMA. Published online September 10, 2020. doi:10.1001/jama.2020.18513PubMedGoogle Scholar
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National Center for Health Statistics. National Health Interview Survey. US Dept of Health and Human Services; 2016. Accessed September 21, 2020. https://www.cdc.gov/nchs/nhis
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Bureau of Labor Statistics. Occupational employment statistics. Accessed September 21, 2020. https://www.bls.gov/oes/home.htm
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Stokes  EK , Zambrano  LD , Anderson  KN ,  et al.  Coronavirus disease 2019 case surveillance: United States, January 22-May 30, 2020.   MMWR Morb Mortal Wkly Rep. 2020;69(24):759-765. doi:10.15585/mmwr.mm6924e2PubMedGoogle ScholarCrossref
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Bauchner  H , Malani  PN , Sharfstein  J .  Reassuring the public and clinical community about the scientific review and approval of a COVID-19 vaccine.   JAMA. Published online September 10, 2020. doi:10.1001/jama.2020.18860PubMedGoogle Scholar
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Lee  GM , Romero  JR , Bell  BP .  Postapproval vaccine safety surveillance for COVID-19 vaccines in the US.   JAMA. Published online October 16, 2020. doi:10.1001/jama.2020.19692Google Scholar
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