Accepted for Publication: September 2, 2020.
Published: October 30, 2020. doi:10.1001/jamanetworkopen.2020.23934
Open Access: This is an open access article distributed under the terms of the CC-BY License. © 2020 Castro VM et al. JAMA Network Open.
Corresponding Author: Roy H. Perlis, MD, MSc, Center for Quantitative Health, Division of Clinical Research, Massachusetts General Hospital, 185 Cambridge St, 6th Floor, Boston, MA 02114 (rperlis@mgh.harvard.edu).
Author Contributions: Dr Perlis had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Concept and design: All authors.
Acquisition, analysis, or interpretation of data: All authors.
Drafting of the manuscript: All authors.
Critical revision of the manuscript for important intellectual content: All authors.
Statistical analysis: Castro, McCoy.
Administrative, technical, or material support: All authors.
Supervision: Perlis.
Conflict of Interest Disclosures: Dr Perlis has received consulting fees from Burrage Capital, Genomind, RID Ventures, and Takeda. He holds equity in Outermost Therapeutics and Psy Therapeutics. Dr McCoy has received research funding from the Stanley Center at the Broad Institute, the Brain and Behavior Research Foundation, National Institute of Mental Health, National Human Genome Research Institute Home, and Telefonica Alfa. No other disclosures were reported.
Disclaimer: Dr Perlis is an Associate Editor at JAMA Network Open; however, he had no role in the editorial review or decision to accept the manuscript for publication.
Additional Contributions: The authors would like to thank the Partners Research Patient Data Registry and Analytics Enclave team members for their support in making up-to-date electronic health record data available for this research. No financial compensation was provided specifically for this work.