This was not my first seizure, nor will it be my last, but it was the first one when I was acutely aware of the faustian bargains that need to be made when a chronic illness acts up during the time of coronavirus disease 2019 (COVID-19). Four years ago, when I was first diagnosed with an astrocytoma, my synapses were dealing with an electrical storm that my consciousness did not anticipate. I relinquished control to my eventual fate—surgery, chemotherapy, radiation therapy—establishing a new normal.1 But this time, 4 years and a pandemic later, I was an active participant.