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The coronavirus disease 2019 (COVID-19) outbreak substantially reduced cancer clinical trial accrual.1 Many sites temporarily paused enrollment owing to state, local, sponsor, or institutional restrictions intended to prevent the spread of COVID-19.2 Once site and enrollment restrictions lift, it is unclear whether patients will be as willing to participate in clinical research as before the outbreak, especially if community COVID-19 transmission is still occurring. To examine this, we surveyed a large group of cancer survivors about their attitudes toward trial participation during the COVID-19 pandemic.
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Accepted for Publication: September 3, 2020.
Published Online: November 12, 2020. doi:10.1001/jamaoncol.2020.5748
Open Access: This is an open access article distributed under the terms of the CC-BY-NC-ND License. © 2020 Fleury ME et al. JAMA Oncology.
Corresponding Author: Mark E. Fleury, PhD, American Cancer Society Cancer Action Network, 6605 13th Pl NW, Washington, DC 20012 (firstname.lastname@example.org).
Author Contributions: Dr Fleury had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Concept and design: All authors.
Acquisition, analysis, or interpretation of data: All authors.
Drafting of the manuscript: Fleury, Unger.
Critical revision of the manuscript for important intellectual content: All authors.
Statistical analysis: Unger, Farner.
Administrative, technical, or material support: Fleury.
Supervision: Fleury, Unger.
Conflict of Interest Disclosures: None reported.
Funding/Support: Funding for building the survey cohort and survey administration was provided by a grant from Bristol Myers Squibb. Additional funding support was provided by the Public Health Sciences Division of the Fred Hutchinson Cancer Research Center.
Role of the Funder/Sponsor: The funders had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
Additional Contributions: We wish to thank all of the patients and survivors who volunteered their time to complete the survey. Small incentive payment in the form of gift cards was offered for participating.
Additional Information: Ms Farner was employed by the American Cancer Society Cancer Action Network at the time the survey was conducted and the data were analyzed, but she is now affiliated with Josh Bersin Academy.
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