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Use of Real-World Electronic Health Records to Estimate Risk, Risk Factors, and Disparities for COVID-19 in Patients With Cancer

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Article Information

Corresponding Author: Nicole M. Kuderer, MD, Advanced Cancer Research Group, 210 Market Street, Suite 303, Kirkland, WA 98033 (kuderern@gmail.com).

Published Online: December 10, 2020. doi:10.1001/jamaoncol.2020.5461

Author Contributions: Mr Desai and Dr Khaki contributed equally to this work.

Conflict of Interest Disclosures: Dr Khaki reported owning stock in Merck & Co and Sanofi SA within the last 2 years. Dr Kuderer reported receiving research consultant fees from G1 Therapeutics, Inc, Invitae Corporation, BeyondSpring Inc, Spectrum Pharmaceuticals, Inc, Bristol Myers Squibb, Janssen Pharmaceutica, and Total Health outside the submitted work and being a founding member of the COVID-19 and Cancer Consortium (CCC19) and former founding member of the CCC19 steering committee. No other disclosures were reported.

Funding Support: Dr Khaki was supported by training grant T32CA009515 from the National Cancer Institute.

Role of the Funder/Sponsor: The National Cancer Institute had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.

References
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Kuderer  NM , Choueiri  TK , Shah  DP ,  et al; COVID-19 and Cancer Consortium.  Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study.   Lancet. 2020;395(10241):1907-1918. doi:10.1016/S0140-6736(20)31187-9PubMedGoogle ScholarCrossref
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Wang  QQ , Berger  NA , Xu  R .  Analyses of risk, racial disparity, and outcomes among US patients with cancer and COVID-19 infection.  Published online December 10, 2020.  JAMA Oncol. doi:10.1001/jamaoncol.2020.6178Google Scholar
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Lee  LY , Cazier  JB , Angelis  V ,  et al; UK Coronavirus Monitoring Project Team.  COVID-19 mortality in patients with cancer on chemotherapy or other anticancer treatments: a prospective cohort study.   Lancet. 2020;395(10241):1919-1926. doi:10.1016/S0140-6736(20)31173-9 PubMedGoogle ScholarCrossref
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Yehia  BR , Winegar  A , Fogel  R ,  et al.  Association of race with mortality among patients hospitalized with coronavirus disease 2019 (COVID-19) at 92 US hospitals.   JAMA Netw Open. 2020;3(8):e2018039. doi:10.1001/jamanetworkopen.2020.18039 PubMedGoogle Scholar
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Yancy  CW .  COVID-19 and African Americans.   JAMA. 2020;323(19):1891-1892. doi:10.1001/jama.2020.6548 PubMedGoogle ScholarCrossref
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Polite  BN , Gluck  AR , Brawley  OW .  Ensuring equity and justice in the care and outcomes of patients with cancer.   JAMA. 2019;321(17):1663-1664. doi:10.1001/jama.2019.4266 PubMedGoogle ScholarCrossref
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American Association for Cancer Research. AACR Cancer Disparities Progress Report 2020. Published 2020. Accessed September 19, 2020. https://cancerprogressreport.aacr.org/disparities/.
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