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Antibodies, Immunity, and COVID-19

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Article Information

Corresponding Author: Brad Spellberg, MD, 2051 Marengo Street, Los Angeles, CA 90033 (bspellberg@dhs.lacounty.gov).

Published Online: November 24, 2020. doi:10.1001/jamainternmed.2020.7986

Conflict of Interest Disclosures: Dr Spellberg reported personal fees from IQVIA and service on multiple data safety monitoring boards for therapeutics for COVID-19, with no financial interest in the sponsors, products, or outcomes of the trials during the conduct of the study. No other disclosures were reported.

References
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Pollán  M , Pérez-Gómez  B , Pastor-Barriuso  R ,  et al; ENE-COVID Study Group.  Prevalence of SARS-CoV-2 in Spain (ENE-COVID): a nationwide, population-based seroepidemiological study.   Lancet. 2020;396(10250):535-544. PubMedGoogle ScholarCrossref
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Havers  FP , Reed  C , Lim  T ,  et al.  Seroprevalence of Antibodies to SARS-CoV-2 in 10 Sites in the United States, March 23-May 12, 2020.   JAMA Intern Med. 2020. Published online July 21, 2020. doi:10.1001/jamainternmed.2020.4130PubMedGoogle Scholar
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Bajema  KL , Wiegand  RE , Cuffe  K ,  et al.  Estimated SARS-CoV-2 seroprevalence in the United States as of September 2020.   JAMA Intern Med. Published online November 24, 2020. doi:10.1001/jamainternmed.2020.7976Google Scholar
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Fontanet  A , Cauchemez  S .  COVID-19 herd immunity: where are we?   Nat Rev Immunol. 2020;20(10):583-584. PubMedGoogle ScholarCrossref
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US Centers for Disease and Prevention. Epidemiology and prevention of vaccine-preventable diseases. Accessed November 1, 2020. https://www.cdc.gov/vaccines/pubs/pinkbook/index.html
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Tillett  RL , Sevinsky  JR , Hartley  PD ,  et al.  Genomic evidence for reinfection with SARS-CoV-2: a case study.   Lancet Infect Dis. 2020;S1473-3099(20)30764-7.PubMedGoogle Scholar
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Klein  SL , Pekosz  A , Park  HS ,  et al.  Sex, age, and hospitalization drive antibody responses in a COVID-19 convalescent plasma donor population.   J Clin Invest. 2020;130(11):6141-6150. PubMedGoogle ScholarCrossref
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Dörner  T , Radbruch  A .  Antibodies and B cell memory in viral immunity.   Immunity. 2007;27(3):384-392. PubMedGoogle ScholarCrossref
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