Accepted for Publication: December 7, 2020.
Published: January 7, 2021. doi:10.1001/jamanetworkopen.2020.35057
Correction: This article was corrected on February 12, 2021, to fix an error in the Supplement.
Open Access: This is an open access article distributed under the terms of the CC-BY License. © 2021 Johansson MA et al. JAMA Network Open.
Corresponding Author: Jay C. Butler, MD, Office of the Deputy Director for Infectious Diseases, US Centers for Disease Control and Prevention, 1600 Clifton Rd, Mailstop H24-12, Atlanta, GA 30329 (jcb3@cdc.gov).
Author Contributions: Dr Johansson had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Concept and design: Johansson, Quandelacy, Kada, Brooks, Slayton, Butler.
Acquisition, analysis, or interpretation of data: All authors.
Drafting of the manuscript: Johansson, Quandelacy, Brooks, Biggerstaff, Butler.
Critical revision of the manuscript for important intellectual content: Johansson, Kada, Prasad, Steele, Brooks, Slayton, Biggerstaff, Butler.
Statistical analysis: Johansson, Quandelacy, Kada.
Administrative, technical, or material support: Prasad, Steele, Brooks, Biggerstaff, Butler.
Supervision: Johansson, Butler.
Conflict of Interest Disclosures: None reported.
Funding/Support: This work was performed as part of the US Centers for Disease Control and Prevention’s coronavirus disease 2019 response and was supported solely by federal base and response funding.
Role of the Funder/Sponsor: The funder had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
Disclaimer: The findings and conclusions in this report are those of the authors and do not necessarily represent the views of the Centers for Disease Control and Prevention.
4.Zhao
S , Gao
D , Zhuang
Z ,
et al. Estimating the serial interval of the novel coronavirus disease (COVID-19): a statistical analysis using the public data in Hong Kong from January 16 to February 15, 2020.
Front Phys. Published online September 17, 2020. doi:
10.3389/fphy.2020.00347Google Scholar 6.Wei
WE , Li
Z , Chiew
CJ , Yong
SE , Toh
MP , Lee
VJ . Presymptomatic transmission of SARS-CoV-2—Singapore, January 23-March 16, 2020.
MMWR Morb Mortal Wkly Rep. 2020;69(14):411-415. doi:
10.15585/mmwr.mm6914e1Google ScholarCrossref 9.Lee
S , Kim
T , Lee
E ,
et al. Clinical course and molecular viral shedding among asymptomatic and symptomatic patients with SARS-CoV-2 infection in a community treatment center in the Republic of Korea.
JAMA Intern Med. 2020. doi:
10.1001/jamainternmed.2020.3862PubMedGoogle Scholar 10.Benefield
AE , Skrip
LA , Clement
A , Althouse
RA , Chang
S , Althouse
BM . SARS-CoV-2 viral load peaks prior to symptom onset: a systematic review and individual-pooled analysis of coronavirus viral load from 66 studies.
medRxiv. Preprinted published online September 30, 2020. doi:
10.1101/2020.09.28.20202028Google Scholar 11.Byrne
AW , McEvoy
D , Collins
AB ,
et al. Inferred duration of infectious period of SARS-CoV-2: rapid scoping review and analysis of available evidence for asymptomatic and symptomatic COVID-19 cases.
BMJ Open. 2020;10(8):e039856. doi:
10.1136/bmjopen-2020-039856PubMedGoogle Scholar 13.Poletti
P , Tirani
M , Cereda
D ,
et al. Probability of symptoms and critical disease after SARS-CoV-2 infection. arXiv. Preprint published online June 22, 2020. Accessed December 10, 2020.
https://arxiv.org/abs/2006.08471 14.Buitrago-Garcia
D , Egli-Gany
D , Counotte
MJ ,
et al. Occurrence and transmission potential of asymptomatic and presymptomatic SARS-CoV-2 infections: a living systematic review and meta-analysis.
PLoS Med. 2020;17(9):e1003346. doi:
10.1371/journal.pmed.1003346PubMedGoogle Scholar 16.Mc Evoy
D , McAloon
CG , Collins
AB ,
et al. The relative infectiousness of asymptomatic SARS-CoV-2 infected persons compared with symptomatic individuals: a rapid scoping review.
medRxiv. Preprint published online August 1, 2020. doi:
10.1101/2020.07.30.20165084Google Scholar 18.Casey
M , Griffin
J , McAloon
CG ,
et al. Pre-symptomatic transmission of SARS-CoV-2 infection: a secondary analysis using published data.
medRxiv. Preprint published online June 11, 2020. doi:
10.1101/2020.05.08.20094870Google Scholar 19.Byambasuren
O , Dobler
CC , Bell
K ,
et al. Comparison of seroprevalence of SARS-CoV-2 infections with cumulative and imputed COVID-19 cases: systematic review.
medRxiv. Preprint published online October 22, 2020. doi:
10.1101/2020.07.13.20153163Google Scholar