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Screening Athletes for Myocarditis With Cardiac Magnetic Resonance Imaging After COVID-19 Infection—Lessons From an English Philosopher

Educational Objective
To identify the key insights or developments described in this article
1 Credit CME

In 1763, Bayes theorem (“An Essay Towards Solving a Problem in the Doctrine of Chances”), one of the most fundamental principles in probability theory, was published in Philosophical Transactions of the Royal Society.1 In a twist of fate, Thomas Bayes had died 2 years prior to the publication of his lasting legacy, which still resonates throughout modern clinical medicine. Bayes theorem is based on conditional probability, or the probability of an event occurring based on other conditions associated with the event in question.1 Today, bayesian philosophy and consideration of pretest probability remains embedded in the determination of best practices for clinical screening and risk stratification.

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Article Information

Corresponding Author: Jonathan H. Kim, MD, MSc, Division of Cardiology, Emory Clinical Cardiovascular Research Institute, Emory University School of Medicine, 1462 Clifton Road NE, Ste 502, Atlanta, GA 30322 (jonathan.kim@emory.edu).

Published Online: January 14, 2021. doi:10.1001/jamacardio.2020.7463

Conflict of Interest Disclosures: Dr Kim discloses research funding for the study of competitive athletes from the National Institute of Health/National Heart, Lung, and Blood Institute. He receives compensation for his role as team cardiologist from the Atlanta Falcons and received research stipends from the Atlanta Track Club.

References
1.
Bayes  T , Price  R .  An essay towards solving a problem in the doctrine of chances.   Philosophical Transactions of the Royal Society. 1763;53:370-418.Google Scholar
2.
Rajpal  S , Tong  MS , Borchers  J ,  et al.  Cardiovascular magnetic resonance findings in competitive athletes recovering from COVID-19 infection.   JAMA Cardiol. Published September 11, 2020. doi:10.1001/jamacardio.2020.4916PubMedGoogle Scholar
3.
Brito  D , Meester  S , Yanamala  N ,  et al.  High prevalence of pericardial involvement in college student athletes recovering from COVID-19.   JACC Cardiovasc Imaging. 2020;S1936-878X(20)30946-3. doi:10.1016/j.jcmg.2020.10.023 PubMedGoogle Scholar
4.
Kim  JH , Levine  BD , Phelan  D ,  et al.  Coronavirus disease 2019 and the athletic heart: emerging perspectives on pathology, risks, and return to play.   JAMA Cardiol. 2020. doi:10.1001/jamacardio.2020.5890PubMedGoogle Scholar
5.
Starekova  J , Bluemke  DA , Bradham  WS ,  et al.  Evaluation for myocarditis in competitive student athletes recovering from coronavirus disease 2019 with cardiac magnetic resonance imaging.   JAMA Cardiol. Published online January 14, 2021. doi:10.1001/jamacardio.2020.7444Google Scholar
6.
Ferreira  VM , Schulz-Menger  J , Holmvang  G ,  et al.  Cardiovascular magnetic resonance in nonischemic myocardial inflammation: expert recommendations.   J Am Coll Cardiol. 2018;72(24):3158-3176. doi:10.1016/j.jacc.2018.09.072PubMedGoogle ScholarCrossref
7.
Maron  BJ , Udelson  JE , Bonow  RO ,  et al.  Eligibility and disqualification recommendations for competitive athletes with cardiovascular abnormalities: task force 3, hypertrophic cardiomyopathy, arrhythmogenic right ventricular cardiomyopathy and other cardiomyopathies, and myocarditis: a scientific statement from the American Heart Association and American College of Cardiology.   J Am Coll Cardiol. 2015;66(21):2362-2371. doi:10.1016/j.jacc.2015.09.035PubMedGoogle ScholarCrossref
8.
Mavrogeni  S , Bratis  C , Kitsiou  A ,  et al.  CMR assessment of myocarditis in patients with cardiac symptoms during H1N1 viral infection.   JACC Cardiovasc Imaging. 2011;4(3):307-309. doi:10.1016/j.jcmg.2010.08.021PubMedGoogle ScholarCrossref
9.
Silver  N .  The Signal and the Noise; Why So Many Predictions Fail—But Some Don’t. Penguin Press; 2012.
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Credit Designation Statement: The American Medical Association designates this Journal-based CME activity activity for a maximum of 1.00  AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to:

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  • 1.00 credit toward the CME of the American Board of Surgery’s Continuous Certification program

It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting MOC credit.

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