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Public Health

Pregnancy, Postpartum Care, and COVID-19 Vaccination in 2021

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To identify the key insights or developments described in this article
1 Credit CME
JAMA
Published Online: February 8, 2021
JAMA Insights
Sonja A. Rasmussen, MD, MS1,2;
Denise J. Jamieson, MD, MPH3
Author Affiliations
  • 1Departments of Pediatrics and Obstetrics and Gynecology, University of Florida College of Medicine, Gainesville
  • 2Department of Epidemiology, University of Florida College of Public Health and Health Professions and College of Medicine, Gainesville
  • 3Emory University School of Medicine, Department of Gynecology and Obstetrics, Atlanta, Georgia
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More than a year has passed since coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was recognized in China. SARS-CoV-2 has spread rapidly throughout the world and continues to cause major morbidity, mortality, and societal disruption globally. The recent authorization by the US Food and Drug Administration (FDA) of 2 vaccines against COVID-19 has raised hopes for an end to the pandemic, but given the many challenges with vaccine availability, distribution, and hesitancy as well as the emergence of variants that might result in lower vaccine efficacy or overcome natural immunity, it is likely that SARS-CoV-2 will continue to circulate.

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CME Disclosure Statement: Unless noted, all individuals in control of content reported no relevant financial relationships. If applicable, all relevant financial relationships have been mitigated.

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Pregnancy Vaccination Obstetrics Public Health Women's Health Obstetrics and Gynecology Coronavirus (COVID-19)
Article Information

Corresponding Author: Denise J. Jamieson, MD, MPH, Department of Gynecology and Obstetrics, Emory University School of Medicine, Woodruff Memorial Research Bldg, 101 Woodruff Circle, Ste 4208, Atlanta, GA 30322 (djamieson@emory.edu).

Published Online: February 8, 2021. doi:10.1001/jama.2021.1683

Conflict of Interest Disclosures: None reported.

References
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Egerup  P , Fich Olsen  L , Christiansen  AH ,  et al.  Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies at delivery in women, partners, and newborns.   Obstet Gynecol. 2021;137(1):49-55. doi:10.1097/AOG.0000000000004199PubMedGoogle ScholarCrossref
2.
Joseph  NT , Stanhope  KK , Badell  ML ,  et al.  Sociodemographic predictors of SARS-CoV-2 infection in obstetric patients, Georgia, USA.   Emerg Infect Dis. 2020;26(11):2787-2789. PubMedGoogle ScholarCrossref
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Zambrano  LD , Ellington  S , Strid  P ,  et al.  Update: characteristics of symptomatic women of reproductive age with laboratory-confirmed SARS-CoV-2 infection by pregnancy status—United States, January 22-October 3, 2020.   MMWR Morb Mortal Wkly Rep. 2020;69(44):1641-1647. PubMedGoogle ScholarCrossref
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Allotey  J , Stallings  E , Bonet  M ,  et al.  Clinical manifestations, risk factors, and maternal and perinatal outcomes of coronavirus disease 2019 in pregnancy.   BMJ. 2020;370:m3320. PubMedGoogle ScholarCrossref
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Khalil  A , von Dadelszen  P , Draycott  T ,  et al.  Change in the incidence of stillbirth and preterm delivery during the COVID-19 pandemic.   JAMA. 2020;324(7):705-706. doi:10.1001/jama.2020.12746PubMedGoogle ScholarCrossref
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Vivanti  AJ , Vauloup-Fellous  C , Prevot  S ,  et al.  Transplacental transmission of SARS-CoV-2 infection.   Nat Commun. 2020;11(1):3572. PubMedGoogle ScholarCrossref
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Pique-Regi  R , Romero  R , Tarca  AL ,  et al.  Does the human placenta express the canonical cell entry mediators for SARS-CoV-2?   Elife. 2020;9:9. doi:10.7554/eLife.58716PubMedGoogle ScholarCrossref
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Chambers  C , Krogstad  P , Bertrand  K ,  et al.  Evaluation for SARS-CoV-2 in breast milk from 18 infected women.   JAMA. 2020;324(13):1347-1348. PubMedGoogle ScholarCrossref
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Salvatore  CM , Han  JY , Acker  KP ,  et al.  Neonatal management and outcomes during the COVID-19 pandemic.   Lancet Child Adolesc Health. 2020;4(10):721-727. PubMedGoogle ScholarCrossref
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Rasmussen  SA , Kelley  CF , Horton  JP , Jamieson  DJ .  Coronavirus disease 2019 (COVID-19) vaccines and pregnancy: what obstetricians need to know.   Obstet Gynecol. Published online December 23, 2020. doi:10.1097/AOG.0000000000004290PubMedGoogle Scholar
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Credit Designation Statement: The American Medical Association designates this Journal-based CME activity activity for a maximum of 1.00  AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

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