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SARS-CoV-2 Variants of Concern in the United States—Challenges and Opportunities

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Article Information

Corresponding Author: Henry T. Walke, MD, MPH, Centers for Disease Control and Prevention, 1600 Clifton Rd, Atlanta, GA 30333 (hfw3@cdc.gov).

Published Online: February 17, 2021. doi:10.1001/jama.2021.2294

Conflict of Interest Disclosures: None reported.

References
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World Health Organization. Weekly epidemiological update—2 February 2021. Accessed February 5, 2021. https://www.who.int/publications/m/item/weekly-epidemiological-update---2-february-2021
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Faria  NR , Claro  IM , Candido  D ,  et al. Genomic characterisation of an emergent SARS-CoV-2 lineage in Manaus: preliminary findings. Virological.org. Published January 12, 2021. Accessed January 31, 2021. https://virological.org/t/genomic-characterisation-of-an-emergent-sars-cov-2-lineage-in-manaus-preliminary-findings/586
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Horby  P , Huntley  C , Davies  N ,  et al. NERVTAG note on B.1.1.7 severity. Paper presented at: SAGE meeting report; January 21, 2021. https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/955239/NERVTAG_paper_on_variant_of_concern__VOC__B.1.1.7.pdf
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Wibmer  CK , Ayres  F , Hernamus  T ,  et al.  SARS-CoV-2 501Y.V2 escapes neutralization by South African COVID-19 donor plasma.   BioRxiv. Preprint published online January 19, 2021. doi:10.1101/2021.01.18.427166Google Scholar
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Wang  P , Liu  L , Iketani  S ,  et al.  Increased resistance of SARS-CoV-2 variants B.1.351 and B.1.1.7 to antibody neutralization.   BioRxiv. Preprint published online January 26, 2021. doi:10.1101/2021.01.25.428137Google Scholar
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Galloway  SE , Paul  P , MacCannell  DR ,  et al.  Emergence of SARS-CoV-2 B.1.1.7 lineage—United States, December 29, 2020-January 12, 2021.   MMWR Morb Mortal Wkly Rep. 2021;70(3):95-99. doi:10.15585/mmwr.mm7003e2 PubMedGoogle ScholarCrossref
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Washington  NL , Gangavarapu  K , Zeller  M ,  et al.  Genomic epidemiology identifies emergence and rapid transmission of SARS-CoV-2 B.1.1.7 in the United States.   medRxiv. Preprint published online February 7, 2021. doi:10.1101/2021.02.06.21251159Google Scholar
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Firestone  MJ ,  et al.  First identified cases of SARS-CoV-2 variant B.1.1.7 in Minnesota—December 2020–January 2021.   MMWR Morb Mortal Wkly Rep. Published online February 17, 2021. doi:10.15585/mmwr.mm7008e1Google Scholar
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Mwenda  M , Saasa  N , Sinyange  N ,  et al.  Detection of B.1.351 SARS-CoV-2 variant strain—Zambia, December 2020.   MMWR Morb Mortal Wkly Rep. Published online February 17, 2021. doi:10.15585/mmwr.mm7008e2Google Scholar
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