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Incidence of 30-Day Venous Thromboembolism in Adults Tested for SARS-CoV-2 Infection in an Integrated Health Care System in Northern California

Educational Objective
To identify the key insights or developments described in this article
1 Credit CME

Hospitalization for COVID-19 is associated with high rates of venous thromboembolism (VTE).1 Whether SARS-CoV-2 infection affects the risk of VTE outside of the hospital setting remains poorly understood. We report on the 30-day incidence of outpatient and hospital-associated VTE following SARS-CoV-2 testing among adult members of the Kaiser Permanente Northern California health plan.

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CME Disclosure Statement: Unless noted, all individuals in control of content reported no relevant financial relationships. If applicable, all relevant financial relationships have been mitigated.

Article Information

Accepted for Publication: February 1, 2021.

Published Online: April 5, 2021. doi:10.1001/jamainternmed.2021.0488

Correction: This article was corrected on October 18, 2021, to fix a typographical error in the corresponding author’s email address.

Corresponding Author: Nareg H. Roubinian, MD, Division of Research, Kaiser Permanente Northern California, 2000 Broadway, Oakland, CA 94612 (nareg.h.roubinian@kp.org).

Author Contributions: Dr Roubinian and Ms Dusendang had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.

Concept and design: All authors.

Acquisition, analysis, or interpretation of data: Roubinian, Dusendang, Mark, Vinson, Schmittdiel, Pai.

Drafting of the manuscript: Roubinian, Dusendang, Liu.

Critical revision of the manuscript for important intellectual content: Roubinian, Dusendang, Mark, Vinson, Schmittdiel, Pai.

Statistical analysis: Roubinian, Dusendang, Schmittdiel.

Obtained funding: Roubinian.

Administrative, technical, or material support: Liu, Schmittdiel, Pai.

Supervision: Roubinian, Schmittdiel.

Conflict of Interest Disclosures: Dr Roubinian reported grants from the National Institutes of Health and the National Heart, Lung, and Blood Institute (R01HL126130) during the conduct of the study. Dr Liu reported grants from the National Institute of General Medical Sciences (R35GM128672) during the conduct of the study. No other disclosures were reported.

Funding/Support: Funding for this work was provided by The Permanente Medical Group Delivery Science and Applied Research Program.

Role of the Funder/Sponsor: The funder had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.

AMA CME Accreditation Information

Credit Designation Statement: The American Medical Association designates this Journal-based CME activity activity for a maximum of 1.00  AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to:

  • 1.00 Medical Knowledge MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program;;
  • 1.00 Self-Assessment points in the American Board of Otolaryngology – Head and Neck Surgery’s (ABOHNS) Continuing Certification program;
  • 1.00 MOC points in the American Board of Pediatrics’ (ABP) Maintenance of Certification (MOC) program;
  • 1.00 Lifelong Learning points in the American Board of Pathology’s (ABPath) Continuing Certification program; and
  • 1.00 credit toward the CME of the American Board of Surgery’s Continuous Certification program

It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting MOC credit.

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