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On December 20, 2020, Israel initiated a national vaccination program against COVID-19. One prioritized group was health care workers, many of whom are breastfeeding women.1 Despite the fact that the vaccine trial did not include this population2 and no other vaccine-related safety data had been published, breastfeeding women belonging to risk groups were encouraged to receive the vaccine.3 The Centers for Disease Control and Prevention has also recommended that breastfeeding women belonging to vaccine-target groups be immunized.4 We investigated whether maternal immunization results in secretion of SARS-CoV-2 antibodies into breast milk and evaluated any potential adverse events among women and their infants.
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CME Disclosure Statement: Unless noted, all individuals in control of content reported no relevant financial relationships. If applicable, all relevant financial relationships have been mitigated.
Corresponding Author: Ilan Youngster, MD, MMSc, Pediatric Infectious Diseases Unit and the Center for Microbiome Research, Shamir Medical Center, Zerifin 70300, Israel (email@example.com).
Accepted for Publication: March 30, 2021.
Published Online: April 12, 2021. doi:10.1001/jama.2021.5782
Author Contributions: Dr Youngster had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. Dr Perl and Ms Uzan-Yulzari contributed equally as co–first authors. Mr Rinott and Dr Youngster contributed equally as co–senior authors.
Concept and design: Perl, Uzan-Yulzari, I. Youngster.
Acquisition, analysis, or interpretation of data: All authors.
Drafting of the manuscript: Perl, Uzan-Yulzari, Asiskovich, M. Youngster, Rinott, I. Youngster.
Critical revision of the manuscript for important intellectual content: Klainer, M. Youngster, Rinott, I. Youngster.
Statistical analysis: Rinott, I. Youngster.
Administrative, technical, or material support: Perl, Uzan-Yulzari, Klainer, Asiskovich, M. Youngster.
Supervision: Perl, Rinott, I. Youngster.
Other: Uzan-Yulzari, Klainer.
Conflict of Interest Disclosures: None reported.
Additional Contributions: We thank Elkana Kohn, PhD, and Netanel Agajany, MD (both for data collection) and Dvora Stahi, MSc (for data analysis), all affiliated with Shamir Medical Center, Zerifin, Israel; none was compensated for his or her contributions.
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