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COVID-19 in Pregnant Women and Their Newborn Infants

Educational Objective
To identify the key insights or developments described in this article
1 Credit CME

Pregnant women have long been recognized as a vulnerable population during infectious disease pandemics.1 This was recognized in 1918, during the Spanish influenza pandemic, in which 50% of pregnant women who were infected died. Despite the many advances in critical care since then, similar findings were noted during the 2009 H1N1 pandemic, in which pregnant women were disproportionately more likely to have severe illness, require hospitalization and intensive care, and die than their nonpregnant counterparts.2,3 Similar findings were noted during the more geographically contained novel coronavirus experiences during the past decades, severe acute respiratory syndrome and Middle East respiratory syndrome coronavirus.4 It is therefore predictable that enhanced risks are associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

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Article Information

Corresponding Author: C. Mary Healy, MD, Infectious Diseases Section, Department of Pediatrics, Baylor College of Medicine, 1102 Bates St, Ste 1120, Houston, TX 77030 (chealy@bcm.edu).

Published Online: April 22, 2021. doi:10.1001/jamapediatrics.2021.1046

Conflict of Interest Disclosures: None reported.

References
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2.
Rasmussen  SA , Jamieson  DJ , Uyeki  TM .  Effects of influenza on pregnant women and infants.   Am J Obstet Gynecol. 2012;207(3)(suppl):S3-S8. doi:10.1016/j.ajog.2012.06.068 PubMedGoogle ScholarCrossref
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Mosby  LG , Ellington  SR , Forhan  SE ,  et al.  The Centers for Disease Control and Prevention’s maternal health response to 2009 H1N1 influenza.   Am J Obstet Gynecol. 2011;204(6)(suppl 1):S7-S12. doi:10.1016/j.ajog.2011.02.057 PubMedGoogle ScholarCrossref
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