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Assessment of SARS-CoV-2 Reinfection 1 Year After Primary Infection in a Population in Lombardy, Italy

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Article Information

Accepted for Publication: May 3, 2021.

Published Online: May 28, 2021. doi:10.1001/jamainternmed.2021.2959

Open Access: This is an open access article distributed under the terms of the CC-BY License. © 2021 Vitale J et al. JAMA Internal Medicine.

Corresponding Author: Nicola Mumoli, MD, Department of Internal Medicine, Ospedale Fornaroli; via al Donatore di Sangue 50, 20013 Magenta (MI), Italy (nimumoli@tiscali.it).

Author Contributions: Dr Mumoli had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. Drs Vitale and Mumoli contributed equally to this letter.

Concept and design: Vitale, Mumoli, Clerici, Mazzone.

Acquisition, analysis, or interpretation of data: All authors.

Drafting of the manuscript: Vitale, Mumoli, Clerici.

Critical revision of the manuscript for important intellectual content: Vitale, Mumoli, De Paschale, Evangelista, Cei, Mazzone.

Statistical analysis: Vitale, Mumoli.

Obtained funding: Clerici.

Administrative, technical, or material support: Mumoli, Clerici, De Paschale.

Supervision: Mumoli, Clerici, Evangelista, Mazzone.

Conflict of Interest Disclosures: None reported.

References
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Hall  VJ , Foulkes  S , Charlett  A ,  et al; SIREN Study Group.  SARS-CoV-2 infection rates of antibody-positive compared with antibody-negative health-care workers in England: a large, multicentre, prospective cohort study (SIREN).   Lancet. 2021;397(10283):1459-1469. doi:10.1016/S0140-6736(21)00675-9PubMedGoogle ScholarCrossref
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Hansen  CH , Michlmayr  D , Gubbels  SM , Mølbak  K , Ethelberg  S .  Assessment of protection against reinfection with SARS-CoV-2 among 4 million PCR-tested individuals in Denmark in 2020: a population-level observational study.   Lancet. 2021;397(10280):1204-1212. doi:10.1016/S0140-6736(21)00575-4PubMedGoogle ScholarCrossref
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Harvey  RA , Rassen  JA , Kabelac  CA ,  et al.  Association of SARS-CoV-2 seropositive antibody test with risk of future infection.   JAMA Intern Med. 2021;181(5):672-679. doi:10.1001/jamainternmed.2021.0366PubMedGoogle ScholarCrossref
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US Centers for Disease Control and Prevention. Investigative criteria for suspected cases of SARS-CoV-2 reinfection (ICR). Accessed March 1, 2021. https://www.cdc.gov/coronavirus/2019-ncov/php/invest-criteria.html
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Mumoli  N , Vitale  J , Mazzone  A .  Clinical immunity in discharged medical patients with COVID-19.   Int J Infect Dis. 2020;99:229-230. doi:10.1016/j.ijid.2020.07.065PubMedGoogle ScholarCrossref
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