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Protection Because of Prior SARS-CoV-2 Infection

Educational Objective
To identify the key insights or developments described in this article
1 Credit CME

How much protection against future infections does prior infection with SARS-CoV-2 infection provide? This is an important question for advising individual patients, as well as for projecting future outbreaks of SARS-CoV-2.

In this issue of JAMA Internal Medicine, Vitale and colleagues1 use the results of diagnostic reverse-transcriptase–polymerase chain reaction tests in Lombardy, Italy, to compare the incidence of SARS-CoV-2 infection among persons with prior SARS-CoV-2 infection with persons who tested negative for the virus.

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CME Disclosure Statement: Unless noted, all individuals in control of content reported no relevant financial relationships. If applicable, all relevant financial relationships have been mitigated.

Article Information

Published Online: May 28, 2021. doi:10.1001/jamainternmed.2021.2966

Corresponding Author: Mitchell H. Katz, MD, NYC Health and Hospitals, 125 Worth St, Room 514, New York, NY 10013 (mitchell.katz@nychhc.org).

Conflict of Interest Disclosures: None reported.

References
1.
Vitale  J , Mumoli  N , Clerici  P ,  et al.  Assessment of SARS-CoV-2 reinfection 1 year after primary infection in a population in Lombardy, Italy.   JAMA Intern Med. Published online May 28, 2021. doi:10.1001/jamainternmed.2021.2959Google Scholar
2.
Harvey  RA , Rassen  JA , Kabelac  CA ,  et al.  Association of SARS-CoV-2 seropositive antibody test with risk of future infection.   JAMA Intern Med. 2021;181(5):672-679. doi:10.1001/jamainternmed.2021.0366PubMedGoogle ScholarCrossref
3.
Spellberg  B , Nielsen  TB , Casadevall  A .  Antibodies, immunity, and COVID-19.   JAMA Intern Med. 2021;181(4):460-462. doi:10.1001/jamainternmed.2020.7986PubMedGoogle ScholarCrossref
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