Improving the Assessment of COVID-19–Associated Posttraumatic Stress Disorder—Reply | Psychiatry and Behavioral Health | JN Learning | AMA Ed Hub [Skip to Content]
[Skip to Content Landing]

Improving the Assessment of COVID-19–Associated Posttraumatic Stress Disorder—Reply

Educational Objective
To identify the key insights or developments described in this article
1 Credit CME

In Reply We thank Marx and colleagues for their thoughtful comment on our recent article investigating the prevalence of posttraumatic stress disorder (PTSD) in postacute COVID-19 illness.1 We fully agree with the authors on the importance of assessing COVID-19–associated PTSD through the criterion-standard Clinician Administered PTSD Scale for DSM-5 (CAPS-5).2 Based on the CAPS-5, we found a 30.2% prevalence of PTSD in patients after acute COVID-19. Our results partly match the pooled PTSD prevalence of 21.94% (95% CI, 9.37-43.31) found in the meta-analysis by Cénat et al,3 which Marx and colleagues cited. However, this meta-analysis3 pooled actual patients with individuals from the general population. Hence, the higher PTSD prevalence found in our study in patients who experienced acute COVID-19 illness is not surprising and in line with the rate of 32.2% (95% CI, 23.7-42.0) reported by Rogers et al4 in postacute patients after previous coronavirus epidemics. Because the field is rapidly expanding, it is likely that many studies will be added and used to meta-analyze and synthesize published evidence.

Sign in to take quiz and track your certificates

Buy This Activity

JN Learning™ is the home for CME and MOC from the JAMA Network. Search by specialty or US state and earn AMA PRA Category 1 CME Credit™ from articles, audio, Clinical Challenges and more. Learn more about CME/MOC

Article Information

Corresponding Author: Delfina Janiri, MD, Department of Psychiatry, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Largo Francesco Vito 1, 00168 Rome, Italy (delfina.janiri@uniroma1.it).

Published Online: June 2, 2021. doi:10.1001/jamapsychiatry.2021.1126

Conflict of Interest Disclosures: Dr Sani reports personal fees from Janssen, Angelini Spa, and Lundbeck. No other disclosures were reported.

References
1.
Janiri  D , Carfì  A , Kotzalidis  GD , Bernabei  R , Landi  F , Sani  G ; Gemelli Against COVID-19 Post-Acute Care Study Group.  Posttraumatic stress disorder in patients after severe COVID-19 infection.   JAMA Psychiatry. Published online February 18, 2021. doi:10.1001/jamapsychiatry.2021.0109PubMedGoogle Scholar
2.
Weathers  FW , Blake  DD , Schnurr  PP , Kaloupek  DG , Marx  BP , Keane  TM .  The Clinician-Administered PTSD Scale for DSM-5 (CAPS-5). Washington, DC: US Department of Veterans Affairs, National Center for PTSD, 2013. https://www.ptsd.va.gov/professional/assessment/adult-int/caps.asp
3.
Cénat  JM , Blais-Rochette  C , Kokou-Kpolou  CK ,  et al.  Prevalence of symptoms of depression, anxiety, insomnia, posttraumatic stress disorder, and psychological distress among populations affected by the COVID-19 pandemic: a systematic review and meta-analysis.   Psychiatry Res. 2021;295:113599. doi:10.1016/j.psychres.2020.113599 PubMedGoogle Scholar
4.
Rogers  JP , Chesney  E , Oliver  D ,  et al.  Psychiatric and neuropsychiatric presentations associated with severe coronavirus infections: a systematic review and meta-analysis with comparison to the COVID-19 pandemic.   Lancet Psychiatry. 2020;7(7):611-627. doi:10.1016/S2215-0366(20)30203-0 PubMedGoogle ScholarCrossref
5.
Weathers  FW , Blake  DD , Schnurr  PP ,  et al.  Life events checklist 5 (LEC-5). National Center for Posttraumatic Stress Disorder; 2013.
6.
Woolf  SH , Chapman  DA , Lee  JH .  COVID-19 as the Leading Cause of Death in the United States.   JAMA. 2021;325(2):123-124. doi:10.1001/jama.2020.24865PubMedGoogle Scholar
If you are not a JN Learning subscriber, you can either:
Subscribe to JN Learning for one year
Buy this activity
jn-learning_Modal_Multimedia_LoginSubscribe_Purchase
Close
If you are not a JN Learning subscriber, you can either:
Subscribe to JN Learning for one year
Buy this activity
jn-learning_Modal_Multimedia_LoginSubscribe_Purchase
Close
With a personal account, you can:
  • Access free activities and track your credits
  • Personalize content alerts
  • Customize your interests
  • Fully personalize your learning experience
Education Center Collection Sign In Modal Right
Close

Name Your Search

Save Search
Close
With a personal account, you can:
  • Track your credits
  • Personalize content alerts
  • Customize your interests
  • Fully personalize your learning experience
jn-learning_Modal_SaveSearch_NoAccess_Purchase
Close

Lookup An Activity

or

Close

My Saved Searches

You currently have no searches saved.

Close
With a personal account, you can:
  • Access free activities and track your credits
  • Personalize content alerts
  • Customize your interests
  • Fully personalize your learning experience
Education Center Collection Sign In Modal Right
Close