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Trends in Respiratory Virus Infections During the COVID-19 Pandemic in Singapore, 2020

Educational Objective
To identify the key insights or developments described in this article
1 Credit CME

The COVID-19 pandemic brought unprecedented challenges to the world. Many jurisdictions implemented control measures, such as border closures, lockdowns, school and business closures, travel restrictions, mask wearing, and social distancing. This was associated with changes in the prevalence of other respiratory viruses, predominantly influenza viruses1,2 but others as well.3

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CME Disclosure Statement: Unless noted, all individuals in control of content reported no relevant financial relationships. If applicable, all relevant financial relationships have been mitigated.

Article Information

Accepted for Publication: May 4, 2021.

Published: June 28, 2021. doi:10.1001/jamanetworkopen.2021.15973

Open Access: This is an open access article distributed under the terms of the CC-BY License. © 2021 Wan WY et al. JAMA Network Open.

Corresponding Author: Matthias Maiwald, MD, Department of Pathology and Laboratory Medicine, KK Women’s and Children’s Hospital, 100 Bukit Timah Rd, Singapore 229899, Singapore (matthias.maiwald@singhealth.com.sg).

Author Contributions: Drs Wan and Maiwald had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.

Concept and design: Wan, Thoon, Chan, Maiwald.

Acquisition, analysis, or interpretation of data: All authors.

Drafting of the manuscript: Wan, Maiwald.

Critical revision of the manuscript for important intellectual content: All authors.

Statistical analysis: Wan, Ramasamy.

Administrative, technical, or material support: Wan, Loo, Chan, Oon, Maiwald.

Supervision: Oon, Maiwald.

Conflict of Interest Disclosures: None reported.

Additional Contributions: We thank the Department of Laboratory Medicine, National University Hospital, Singapore, for the generous provision of the respiratory virus data from the hospital.

References
1.
Cowling  BJ , Ali  ST , Ng  TWY ,  et al.  Impact assessment of non-pharmaceutical interventions against coronavirus disease 2019 and influenza in Hong Kong: an observational study.   Lancet Public Health. 2020;5(5):e279-e288. doi:10.1016/S2468-2667(20)30090-6 PubMedGoogle ScholarCrossref
2.
Fricke  LM , Glöckner  S , Dreier  M , Lange  B .  Impact of non-pharmaceutical interventions targeted at COVID-19 pandemic on influenza burden—a systematic review.   J Infect. 2021;82(1):1-35. doi:10.1016/j.jinf.2020.11.039 PubMedGoogle ScholarCrossref
3.
Partridge  E , McCleery  E , Cheema  R ,  et al.  Evaluation of seasonal respiratory virus activity before and after the statewide COVID-19 shelter-in-place order in Northern California.   JAMA Netw Open. 2021;4(1):e2035281. doi:10.1001/jamanetworkopen.2020.35281 PubMedGoogle Scholar
4.
Health Hub. Influenza. Accessed November 4, 2020. https://www.healthhub.sg/a-z/diseases-and-conditions/103/topics_influenza
5.
Hale  T , Atav  T , Hallas  L , Kira  B , Phillips  T , Petherick  A ,  et al. Coronavirus government response tracker. Accessed January 4, 2021. https://www.bsg.ox.ac.uk/research/research-projects/coronavirus-government-response-tracker
6.
Kutter  JS , Spronken  MI , Fraaij  PL , Fouchier  RAM , Herfst  S .  Transmission routes of respiratory viruses among humans.   Curr Opin Virol. 2018;28:142-151. doi:10.1016/j.coviro.2018.01.001 PubMedGoogle ScholarCrossref
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