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Olfactory dysfunction (OD) is one of the earliest and strongest predictors of COVID-19 infection, and thus is promising as a disease screening tool.1,2 Compared with objective testing, subjective olfactory assessments significantly underreport OD.3,4 Thus, an inexpensive, quick, and sensitive method of assessing olfaction may be beneficial for the early diagnosis and spread prevention of COVID-19. In this study, we evaluate the feasibility of a novel, objective olfactory test as part of an initial screening for COVID-19 in adults with unknown disease status.
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Accepted for Publication: May 26, 2021.
Published Online: July 15, 2021. doi:10.1001/jamaoto.2021.1456
Corresponding Author: Carol H. Yan, MD, Division of Otolaryngology–Head and Neck Surgery, Department of Surgery, University of California, San Diego, 9350 Campus Point Dr, Mail Code 0970, La Jolla, CA 92037 (firstname.lastname@example.org).
Author Contributions: Dr Yan had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Concept and design: Said, P. Davis, S. A. Davis, S. Davis, Yan.
Acquisition, analysis, or interpretation of data: Said, S. A. Davis, Smart, S. Davis, Yan.
Drafting of the manuscript: Said, S. A. Davis, Yan.
Critical revision of the manuscript for important intellectual content: Said, P. Davis, Smart, S. Davis, Yan.
Statistical analysis: Said, Yan.
Administrative, technical, or material support: Said, P. Davis, S. A. Davis, S. Davis, Yan.
Conflict of Interest Disclosures: Dr Davis is the founder of SAFER Diagnostics. No other disclosures were reported.
Funding/Support: This work was supported by SAFER Diagnostics.
Role of the Funder/Sponsor: SAFER Diagnostics had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
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