Quantification of Antibodies Against SARS-CoV-2 in Breast Milk of Women Who Received an mRNA Vaccine | Breastfeeding | JN Learning | AMA Ed Hub [Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 35.153.100.128. Please contact the publisher to request reinstatement.
[Skip to Content Landing]

Quantification of Specific Antibodies Against SARS-CoV-2 in Breast Milk of Lactating Women Vaccinated With an mRNA Vaccine

Educational Objective
To identify the key insights or developments described in this article
1 Credit CME

Sign in to take quiz and track your certificates

Buy This Activity

CME Disclosure Statement: Unless noted, all individuals in control of content reported no relevant financial relationships. If applicable, all relevant financial relationships have been mitigated.

Article Information

Accepted for Publication: June 8, 2021.

Published: August 11, 2021. doi:10.1001/jamanetworkopen.2021.20575

Open Access: This is an open access article distributed under the terms of the CC-BY License. © 2021 Esteve-Palau E et al. JAMA Network Open.

Corresponding Author: Vicens Diaz-Brito, MD, PhD, Department of Infectious Diseases, Parc Sanitari Sant Joan de Déu, 08830 Sant Boi, Barcelona, Spain (vicente.diaz@pssjd.org).

Author Contributions: Drs Diaz-Brito and Esteve-Palau had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.

Concept and design: Esteve-Palau, Diaz-Brito.

Acquisition, analysis, or interpretation of data: All authors.

Drafting of the manuscript: Esteve-Palau, Casadevall, Diaz-Brito.

Critical revision of the manuscript for important intellectual content: All authors.

Statistical analysis: Esteve-Palau, Casadevall, Diaz-Brito.

Obtained funding: Esteve-Palau.

Administrative, technical, or material support: Esteve-Palau, Casadevall.

Supervision: Esteve-Palau, Gonzalez-Cuevas, Guerrero, Garcia-Terol, Alvarez, Diaz-Brito.

Conflict of Interest Disclosures: None reported.

Additional Contributions: We acknowledge the samples collection effort of Geneva Garcia, RN, from the Department of Infectious Diseases at Parc Sanitari Sant Joan de Déu. No additional compensation was provided.

References
1.
Pace  RM , Williams  JE , Järvinen  KM ,  et al.  Characterization of SARS-CoV-2 RNA, antibodies, and neutralizing capacity in milk produced by women with COVID-19.   mBio. 2021;12(1):e03192-e20. doi:10.1128/mBio.03192-20PubMedGoogle ScholarCrossref
2.
Perl  SH , Uzan-Yulzari  A , Klainer  H ,  et al.  SARS-CoV-2-specific antibodies in breast milk after COVID-19 vaccination of breastfeeding women.   JAMA. 2021;325(19):2013-2014. doi:10.1001/jama.2021.5782PubMedGoogle ScholarCrossref
3.
Collier  AY , McMahan  K , Yu  J ,  et al.  Immunogenicity of COVID-19 mRNA vaccines in pregnant and lactating women.   JAMA. 2021;325(23):2370-2380. doi:10.1001/jama.2021.7563PubMedGoogle ScholarCrossref
4.
Pace  RM , Williams  JE , Järvinen  KM ,  et al.  Characterization of SARS-CoV-2 RNA, antibodies, and neutralizing capacity in milk produced by women with COVID-19.   mBio. 2021;12(1):e03192-20. doi:10.1128/mBio.03192-20PubMedGoogle Scholar
5.
Deeks  JJ , Dinnes  J , Takwoingi  Y ,  et al; Cochrane COVID-19 Diagnostic Test Accuracy Group.  Antibody tests for identification of current and past infection with SARS-CoV-2.   Cochrane Database Syst Rev. 2020;6:CD013652. doi:10.1002/14651858.CD013652PubMedGoogle Scholar
6.
Demers-Mathieu  V , Do  DM , Mathijssen  GB ,  et al.  Difference in levels of SARS-CoV-2 S1 and S2 subunits- and nucleocapsid protein-reactive SIgM/IgM, IgG and SIgA/IgA antibodies in human milk.   J Perinatol. 2020;41(4):850-859. doi:10.1038/s41372-020-00805-wPubMedGoogle ScholarCrossref
If you are not a JN Learning subscriber, you can either:
Subscribe to JN Learning for one year
Buy this activity
jn-learning_Modal_Multimedia_LoginSubscribe_Purchase
Close
If you are not a JN Learning subscriber, you can either:
Subscribe to JN Learning for one year
Buy this activity
jn-learning_Modal_Multimedia_LoginSubscribe_Purchase
Close
With a personal account, you can:
  • Access free activities and track your credits
  • Personalize content alerts
  • Customize your interests
  • Fully personalize your learning experience
Education Center Collection Sign In Modal Right
Close

Name Your Search

Save Search
Close
With a personal account, you can:
  • Track your credits
  • Personalize content alerts
  • Customize your interests
  • Fully personalize your learning experience
jn-learning_Modal_SaveSearch_NoAccess_Purchase
Close

Lookup An Activity

or

Close

My Saved Searches

You currently have no searches saved.

Close
With a personal account, you can:
  • Access free activities and track your credits
  • Personalize content alerts
  • Customize your interests
  • Fully personalize your learning experience
Education Center Collection Sign In Modal Right
Close