Accepted for Publication: May 20, 2021.
Published Online: August 19, 2021. doi:10.1001/jamaoncol.2021.3067
Corresponding Author: Kerry S. Courneya, PhD, Faculty of Kinesiology, Sport, and Recreation, University of Alberta, 1-113 University Hall, Edmonton, Alberta T6G 2H9, Canada (kerry.courneya@ualberta.ca).
Author Contributions: Dr Kang and Prof Courneya had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.
Concept and design: Kang, Fairey, Boulé, Courneya.
Acquisition, analysis, or interpretation of data: All authors.
Drafting of the manuscript: Kang.
Critical revision of the manuscript for important intellectual content: All authors.
Statistical analysis: Kang, Fairey, Boulé, Courneya.
Obtained funding: Kang, Courneya.
Administrative, technical, or material support: Kang, Fairey, Wharton, Courneya.
Supervision: Kang, Fairey, Boulé, Field, Courneya.
Conflict of Interest Disclosures: None reported.
Funding/Support: This study was supported by grant 389507 from the Canadian Institutes of Health Research and grant D2017-1820 from Prostate Cancer Canada. Prof Courneya was supported by the Canada Research Chairs Program. Dr Kang was supported by the Alberta Innovates Graduate Studentship. Exercise equipment was donated by Apple Fitness, Edmonton, Alberta, Canada.
Role of the Funder/Sponsor: The funders had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
Data Sharing Statement: See Supplement 3.
Additional Contributions: We acknowledge the support of the following individuals: Niels-Erik Jacobsen, MD, Michael Chetner, MD, Sarah Rayner, RN, and Nupur Agarwal, CCPA, Northern Alberta Urology Center, assisted with patient recruitment; Sue Goruk, PhD, and Dhruvesh Patel, BSc, University of Alberta, assisted with blood assays; and Andria Morielli, PhD, Terri Wood, BSc, Ki-Yong An, PhD, Fernanda Arthuso, MSc, Stephanie Ntoukas, BSc, Spencer Allen, BSc, and Morgan Corbett, BSc, University of Alberta, assisted with exercise testing and intervention. These individuals received no additional compensation, outside of their usual salary, for their contributions. We also thank the study participants for their time and commitment.