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Association Between Exposure Characteristics and the Risk for COVID-19 Infection Among Health Care Workers With and Without BNT162b2 Vaccination

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CME Disclosure Statement: Unless noted, all individuals in control of content reported no relevant financial relationships. If applicable, all relevant financial relationships have been mitigated.

Article Information

Accepted for Publication: July 13, 2021.

Published: September 1, 2021. doi:10.1001/jamanetworkopen.2021.25394

Open Access: This is an open access article distributed under the terms of the CC-BY License. © 2021 Oster Y et al. JAMA Network Open.

Corresponding Author: Yonatan Oster, MD, Department of Clinical Microbiology and Infectious Diseases, Hadassah Hebrew University Medical Center, Ein-Kerem, POB 12000, Jerusalem 91120, Israel (yonatano@hadassah.org.il).

Author Contributions: Drs Oster and Benenson contributed equally to the study, had full access to all of the data in the study, and take responsibility for the integrity of the data and the accuracy of the data analysis.

Concept and design: Oster, Benenson, Buda, Nir-Paz, Strahilevitz, Cohen.

Acquisition, analysis, or interpretation of data: Oster, Benenson, Yochi Harpaz, Cohen.

Drafting of the manuscript: Oster, Benenson, Nir-Paz, Cohen.

Critical revision of the manuscript for important intellectual content: Benenson, Yochi Harpaz, Buda, Nir-Paz, Strahilevitz, Cohen.

Statistical analysis: Cohen.

Administrative, technical, or material support: Benenson, Buda.

Supervision: Benenson, Strahilevitz, Cohen.

Conflict of Interest Disclosures: Dr Nir-Paz reported serving as a paid consultant for BiomX and receiving grants from Technophage outside the submitted work. No other disclosures were reported.

Funding/Support: The publication of this study was partially funded by Hadassah-Hebrew University Medical Center internal funds.

Role of the Funder/Sponsor: Hadassah-Hebrew University Medical Center had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.

Additional Contributions: The authors thank the dedicated nurses of the Unit for Infection Prevention and Control for conducting the epidemiologic investigations (in alphabetical order): Ayelet Favor, RN, MPH, Ilana Gross RN, MPH, Kami Harpaz RN, MPH, Jana Hen, RN, MHA, Miriam Ottolenghi, RN, MEM, Ela Radbogin, RN, MA, Nechamat Reichman, RN, Naama Ronen, RN, MPH, Nechama Shilo, RN, MPH, and Carole Slama, RN, MA. No additional compensation was received for this work.

References
1.
Haas  EJ , Angulo  FJ , McLaughlin  JM ,  et al.  Impact and effectiveness of mRNA BNT162b2 vaccine against SARS-CoV-2 infections and COVID-19 cases, hospitalisations, and deaths following a nationwide vaccination campaign in Israel: an observational study using national surveillance data.   Lancet. 2021;397(10287):1819-1829. Published online May 5, 2021. doi:10.1016/S0140-6736(21)00947-8PubMedGoogle ScholarCrossref
2.
When you’ve been fully vaccinated: how to protect yourself and others. Centers for Disease Control and Prevention. Updated July 27, 2021. Accessed May 9, 2021. https://www.cdc.gov/coronavirus/2019-ncov/vaccines/fully-vaccinated.html
3.
Keehner  J , Horton  LE , Pfeffer  MA ,  et al.  SARS-CoV-2 infection after vaccination in health care workers in California.   N Engl J Med. 2021;384(18):1774-1775. doi:10.1056/NEJMc2101927 PubMedGoogle ScholarCrossref
4.
Benenson  S , Oster  Y , Cohen  MJ , Nir-Paz  R .  BNT162b2 mRNA COVID-19 vaccine effectiveness among health care workers.   N Engl J Med. 2021;384(18):1775-1777. doi:10.1056/NEJMc2101951 PubMedGoogle ScholarCrossref
5.
Munitz  A , Yechezkel  M , Dickstein  Y , Yamin  D , Gerlic  M .  BNT162b2 vaccination effectively prevents the rapid rise of SARS-CoV-2 variant B.1.1.7 in high-risk populations in Israel.   Cell Rep Med. 2021;2(5):100264. doi:10.1016/j.xcrm.2021.100264 PubMedGoogle Scholar
6.
Kahlert  CR , Persi  R , Güsewell  S ,  et al.  Non-occupational and occupational factors associated with specific SARS-CoV-2 antibodies among hospital workers - A multicentre cross-sectional study.   Clin Microbiol Infect. 2021;S1198-743X(21)00236-6. Published online May 19, 2021. doi:10.1016/j.cmi.2021.05.014PubMedGoogle Scholar
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